New CT-Based method could predict hip fractures before they happen
NCT ID NCT06270758
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks if a computer tool called BBCT-hip can accurately predict the risk of breaking the thigh bone (femur) when a person falls. Researchers will enroll 300 postmenopausal women with osteoporosis—150 who have already had a fracture and 150 who have not. All will get a CT scan, and the tool will use the scan plus height and weight to estimate fracture risk. The goal is to see if BBCT-hip can tell apart those at higher risk, which could help prevent future fractures.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2023
- Expected to finish
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Nov 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Resident in Emilia Romagna, Italy
- Ages
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65 to 85 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * caucasic post-menopausal women resident in Emilia-Romagna * menopause (\>= 45 years) Exclusion Criteria: * tumours * not free living * Chronic diseases with severe organ failure / endocrine diseases of parathyroid, thyroid, adrenal gland / intestinal malabsorption, osteomalacia / Paget bone / rheumatoid arthritis. Neurodegenerative diseases * Long-term continuous therapy (\>3 months) with corticosteroids and proton pump inhibitors or aromatase inhibitors * Previous femur fractures * Presence of hip/knee prosthesis only for the fracturegroup: * presence of fixation devices after the fracture * femur fracture due to high energy trauma
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Rizzoli Orthopaedic Institute
RECRUITINGBologna, 40136, Italy
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Rizzoli Orthopaedic Institute
RECRUITINGBologna, 40136, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Pregnancy hormone hCG may hold clues to bone and gland health
- Simple scan mistakes may skew osteoporosis diagnoses
- Can better posture strengthen the pelvic floor in osteoporosis?
- Could exercise be the key to stronger bones in women?
- Robotic legs may help rebuild bone in people with spinal cord injury
- Could a simple education program stop the cycle of fractures in the elderly?