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Can we predict who benefits from heart failure device therapy?

NCT ID NCT06977217

First seen Jun 16, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This study enrolls 270 heart failure patients without a specific heart electrical pattern (non-LBBB) who are getting a cardiac resynchronization therapy defibrillator (CRT-D). Researchers want to find out which factors predict a good response to the device, measured by heart function improvement after 12 months. The goal is to better identify patients who will benefit most from this therapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cardiac resynchronization therapy with a defibrillator (CRT-D)

What this could lead to

If successful, this study could help doctors predict which heart failure patients without a specific ECG pattern will benefit most from CRT-D, improving treatment decisions.

What could go wrong

This is an observational study, not a treatment trial. It aims to find predictors, not test a new therapy. Results may not apply to all patients or change current practice.

Conditions

The condition(s) this trial relates to.

cardiomyopathy heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.