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Why does labetalol fail in severe preeclampsia? new study aims to find out

NCT ID NCT07547046

First seen May 02, 2026 · Last updated Jun 22, 2026 · Updated 10 times

Summary

Severe preeclampsia is a dangerous pregnancy complication that can cause high blood pressure, harming both mother and baby. This observational study will follow 350 women to identify factors that make blood pressure control with the drug labetalol fail. By understanding these factors, doctors hope to predict treatment failure and adjust care more quickly.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Agen-Nerac

    Nérac, France

    Contact

  • CH de Roubaix

    Roubaix, France

    Contact Email: •••••@•••••

  • CHRU Nancy

    Nancy, France

    Contact Email: •••••@•••••

  • CHU Bordeaux

    Bordeaux, France

    Contact

  • CHU Carémeau

    Nîmes, France

    Contact

  • CHU Clermont-Ferrand

    Clermont-Ferrand, France

    Contact Email: •••••@•••••

  • CHU Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant

    Lyon, France

    Contact

  • CHU Lille

    Lille, France

    Contact Email: •••••@•••••

  • CHU Martinique

    Martigues, France

    Contact Email: •••••@•••••

  • Hôpital Antoine Béclère

    Clamart, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Armand-Trousseau

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Bicêtre

    Le Kremlin-Bicêtre, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Cochin Port Royal

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Necker

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

labetalol

What this could lead to

If successful, this study could help doctors identify which women with severe preeclampsia are less likely to respond to labetalol, allowing for faster, more personalized treatment.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test a new therapy. It may only identify associations, not causes, and results may not apply to all populations.

Conditions

The condition(s) this trial relates to.

preeclampsia severe pre-eclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.