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Could a simple water pill get moms home faster after severe preeclampsia?

NCT ID NCT07648251

Symptom relief Sponsor: Universidad Nacional Autonoma de Honduras Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a common water pill (furosemide) can help women with severe preeclampsia recover faster after childbirth and leave the hospital sooner. About 186 women will receive either furosemide or a placebo starting 12 hours after delivery. The goal is to see if the drug reduces hospital stay without causing harm.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
furosemide (a water pill)
What this could lead to
If it works, this could help women with severe preeclampsia leave the hospital sooner after giving birth, reducing time away from their newborns.
What could go wrong
This is a small, early-phase trial (186 people) in two hospitals in Honduras, so results may not apply everywhere. Furosemide can cause dehydration or electrolyte imbalances.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 186 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

14 to 49 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Signed informed consent (assent for minors 14-17 years with parental/guardian consent) * Confirmed severe preeclampsia (BP ≥160/110 mmHg, or lower BP with thrombocytopenia, hepatic dysfunction, renal insufficiency, pulmonary edema, or cerebral/visual symptoms) * Postpartum (12-24 hours after delivery, vaginal or cesarean) * Hemodynamically stable (no vasopressors for ≥6 hours) * Preserved diuresis (\>30 mL/hour for ≥6 hours) * Serum creatinine \<0.8 mg/dL Exclusion Criteria: * Current or chronic diuretic use (before or during pregnancy) * Known allergy to sulfonamides or furosemide * Active febrile illness * Known chronic kidney disease (eGFR \<60 mL/min/1.73m²) * Participation in another interventional trial * Pregnancy (current - not applicable postpartum, but excludes undiagnosed concurrent pregnancy)

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Conditions

The condition(s) this trial relates to.

hypertensive disorder preeclampsia severe pre-eclampsia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Severe preeclampsia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Escuela

    Tegucigalpa, Francisco Morazán Department, 11101, Honduras

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