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Tablet app tracks eye movements to spot chemo brain

NCT ID NCT05186948

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to develop and validate a tablet-based eye-tracking app to detect cancer-related cognitive impairment, often called 'chemo brain.' Researchers planned to enroll 230 participants, including breast cancer patients scheduled for chemotherapy and healthy volunteers. The app would track eye movements to measure attention and processing speed. However, the study was terminated early, so its effectiveness remains unproven.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Eye-tracking software application
What this could lead to
If successful, this could provide a simple, non-invasive way to detect and monitor brain fog in cancer patients using just a tablet.
What could go wrong
The study was terminated early, so results are limited. It is a small, early-stage development, and the technology may not prove accurate enough for clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

230 people

The number who actually took part.

Started

Mar 2022

Finished

Jan 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Data will be obtained from 200 patients with an initial diagnosis of breast cancer stages I-IIIA and scheduled chemotherapy, fulfilling the eligibility criteria. Data will also be acquired from a group of 30 healthy control participants. Groups will be matched for age and sex.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * For all participants: 1. Able to provide informed consent. 2. Visual acuity sufficient to be able to read the consent form with corrective lenses. 3. Over 18 years of age. 4. English- or French-speaking. * For patients only: 1. Initial diagnosis of breast cancer stage I-IIIA and scheduled chemotherapy 2. First-time cancer diagnosis. 3. ECOG performance \< 2 4. Receiving curative intent chemotherapy: either Adriamycin/Cyclophosphamide for 4 cycles followed by weekly Taxol for 12 cycles or Taxotere/Cyclophosphamide for 4 cycles Exclusion Criteria: * For all participants: 1. Evidence or medical history of neurological/psychiatric issues known to affect movements and oculomotor control. 2. Presence of comorbid neurological conditions to avoid eye movement anomaly confounds (Strabismus, cranial nerve palsy, stroke-causing hemianopsia). 3. Diagnosis of macular edema or other pre-existing ocular conditions that would prevent participants from performing the eye movement assessments. 4. Previous history of cancer or chemotherapy 5. Distant metastases 6. Recent (less than three months from enrollment) start of, change of dose, or irregular use of, new prescription drugs known to influence ocular motor visual function, such as benzodiazepines, antipsychotics and anticonvulsants. Occasional use of benzodiazepines for medical procedures is permitted, at the investigator's discretion, but should not occur within a short time period prior to or during an eye movement assessment. 7. Diagnosis of a substance abuse disorder. 8. Recreational drug use (e.g., alcohol, marijuana) is a potential exclusion criterion that will be determined on an individual basis as per the discretion of the research team. All recreational drug use will be documented.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • McGill University Health Center-Cedar Cancer Center

    Montreal, Quebec, H4A 3J1, Canada

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