New test aims to spot 'Chemo Brain' in breast cancer survivors
NCT ID NCT07582770
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks if a new set of thinking and memory tests can better detect cognitive problems in breast cancer survivors who had chemotherapy. Researchers will compare results from 200 survivors and healthy volunteers to see if the tests are accurate. The goal is to improve diagnosis of cancer-related cognitive impairment, often called 'chemo brain'.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Female breast cancer survivors (N = 100) will be recruited at the European Institute of Oncology (IEO) while, female non-cancer controls (N = 100) will be recruited though an invitation to participate in the study, accompanied by a brief description of its objectives and procedures, that will be disseminated via social media groups, word of mouth and breast cancer patient associations.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 18 and 65 years old * Patient with a previous documented diagnosis of non-metastatic breast cancer (only for breast cancer survivor gruop) * Patient has completed chemotherapy for at least 6 months and for a maximum of 36 months if planned (only for breast cancer survivor gruop) * Understanding of the Italian language and ability to give informed consent Exclusion Criteria: * Presence of brain metastases or history of brain radiation therapy (only for breast cancer survivor gruop) * Patient with previous diagnosis of other malignant tumors in addition to breast cancer (only for breast cancer survivor gruop) * Patient with a previous diagnosis of malignant carcinomas (only for control gruop) * Patient with a history of brain damage with unresolved neurological consequences * Patient with previous or current serious neurological pathologies * Patient with severe psychiatric conditions * Patient with systemic pathologies that could interfere with cognitive abilities * Patient taking medications that have a strong cognitive impact and that have not been stabilized for at least 4 weeks prior to enrollment * Patient with visual or hearing impairments that are not properly corrected * Patient with any disability that might compromise the validity of cognitive tests
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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European Institute of Oncology
Milan, 20435, Italy
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Other studies related to the condition(s) this trial covers.
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- Can a Decades-Old Anti-Inflammatory drug quiet the joint pain that drives women off breast cancer therapy?