AI-Powered blood test could spot five cancers before symptoms show
NCT ID NCT07186296
First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 3 times
Summary
This study is testing a new blood test called EXoPred that uses artificial intelligence and laser technology to find tiny particles from cancer cells. The goal is to detect breast, colon, pancreatic, ovarian, and lung cancers at an early stage. Researchers will enroll 1,400 people aged 45 and older who have or are suspected of having one of these cancers. The test is not yet proven and this study will help refine the algorithm for future use.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- EXoPred diagnostic test (blood test using AI and laser analysis of particles from cells)
- What this could lead to
- If successful, this could lead to a simple blood test that catches multiple cancers early, when they are easier to treat.
- What could go wrong
- This is an early-stage study focused on building and validating the test's algorithm. It may not yet be accurate enough for widespread use, and results need confirmation in larger, more diverse groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study participants will be collected from hospitals/clinical care settings with access to the intended population.
- Ages
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45 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject aged 45 years or older with a biopsy-proven or clinically suspected primary lung, breast, colorectal, pancreatic, or ovarian cancer, based on objective findings such as radiological, serological, endoscopic, or cytological findings, whose blood was collected prior to any systemic or definitive therapy for the cancer. * Subjects who are willing and able to provide written informed consent. * Subjects who are willing and able to comply with the study requirements. Exclusion Criteria: * Any history of cancer diagnosed and treated within 5 years prior to the date of consent. * Subjects with a history of previous cancer treatment via surgical resection, hormonal cancer treatment, chemotherapy, radiotherapy within the past 6 months for recent cancer diagnosis. * Subjects who have any history of an allogeneic bone marrow, stem cell transplant, or solid organ transplant. * Subjects who are pregnant or breastfeeding women. * Subjects who have consented and have undergone treatment in any other cancer related clinical trials withinthe past 6 months. * Subjects who are currently in active treatment for drug abuse. * Subjects who have received any treatment related to lung, breast, colorectal, pancreatic, or ovarian nodules, such as hormones prior to entering the study. * Unsuitable sample for testing due to contamination, hemolysis, etc.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
9 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Albany Stratton VA Medical Center
RECRUITINGAlbany, New York, 12208, United States
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Bronx Veterans Medical Research Foundation
RECRUITINGThe Bronx, New York, 10468, United States
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City of Hope Duarte Cancer Center
RECRUITINGLos Angeles, California, 91010, United States
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John Hopkins University
RECRUITINGBaltimore, Maryland, 21218, United States
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KCTL
RECRUITINGLouisville, Kentucky, 40202, United States
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Lexington VA Healthcare System
RECRUITINGLexington, Kentucky, 40502, United States
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Tibor Rubin VA Medical Center
RECRUITINGLong Beach, California, 90822, United States
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University of Hawaii Cancer Center
RECRUITINGHonolulu, Hawaii, 96813, United States
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VA Hudson Valley Healthcare System
RECRUITINGWappingers Falls, New York, 12590, United States
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