New study: exercise plus therapy may double depression relief
NCT ID NCT07253935
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if adding exercise and education to standard talk therapy helps people with depression feel better. About 112 adults will be split into two groups: one gets therapy alone, the other adds an 8-week program of guided exercise and learning sessions. Researchers will check mood, quality of life, and sleep to see if the combined approach works better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 112 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of depression or dysthymia according to the ICD-11 criteria (including unspecified depressive disorder, code 6A7Z) or DSM-5-TR criteria confirmed by their referring physician. * A patient currently undergoing psychological treatment for depression with a score above the established cutoff in a validated depression questionnaire. Exclusion Criteria: * Pregnancy. * Presence of neurological comorbidities or neurological signs. * Systemic rheumatic diseases, including fibromyalgia. * Central nervous system disorders. * Severe cognitive impairment. * Schizophrenia, psychotic disorders, or bipolar spectrum disorders.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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