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Just move: study tests if exercise boosts strength and mood in kids with cancer

NCT ID NCT05058508

Symptom relief Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 23, 2026 · Updated 4 times

Summary

This study is testing whether a structured exercise program called 'Just Move' can help children and young adults (ages 2–25) with newly diagnosed cancer maintain physical function and improve quality of life during chemotherapy. Participants will either follow a 30-minute exercise routine five times per week or continue their usual activity. The study will measure physical function, side effects, and emotional well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
structured exercise program
What this could lead to
If it works, this could show that regular exercise helps children with cancer stay stronger and feel better during chemotherapy.
What could go wrong
This is a small, early-phase study with only 60 participants, so results may not apply to all children. Exercise may be hard for some kids to complete during treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2024

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

2 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Ages 2-25 at time of consent 2. Subject has newly diagnosed cancer per Investigator, and is planning to undergo chemotherapy for treatment of malignancy for at least 3 full cycles 3. Ability of subject (and/or parent/guardian) to read and understand the English or Spanish language 4. As determined and documented by the enrolling investigator, ability of the subject to understand and comply with study procedures for the entire length of the study 5. Subject has newly diagnosed cancer per Investigator and is planning to undergo chemotherapy, immunotherapy, or other systemically delivered for treatment of malignancy. Subjects are allowed to be enrolled up to 21 days after initiating cancer treatment. 6. Receiving oncologic care at Levine Children's Cancer and Blood Disorders Clinic. 7. Subject is anticipated to receive at least 3 full cycles of chemotherapy or other systemic cancer treatment. 8. Not participating in another clinical trial that precludes participating in additional nondrug clinical trials. Exclusion Criteria: 1. Known cardiac dysfunction that, in the opinion of the investigator, would be unsafe for the child to participate in the exercise program 2. Any other uncontrolled intercurrent illness/medical condition or psychiatric illness/social situations that would limit compliance with study requirements or would be considered unsafe for the child to participate as determined by the Investigator. 3. Recent (within 4 weeks of enrollment) or planned surgery that will result in prolonged limited mobility not amendable to exercise modifications per investigator discretion 4. Primary CNS Tumor 5. Osteosarcoma

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Conditions

The condition(s) this trial relates to.

childhood malignant neoplasm Motor Activity neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pediatric cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Levine Children's Hospital

    RECRUITING

    Charlotte, North Carolina, 28203, United States

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