Which exercise heals the knee tendon best? a Head-to-Head trial
NCT ID NCT07682051
First seen Jul 02, 2026 · Last updated Sep 10, 2026 · Updated 2 times
Summary
This study compares two 12-week exercise programs—eccentric training and heavy-slow resistance training—in 30 adults aged 18–50 with patellar tendinopathy (knee pain lasting over 3 months). Researchers measure changes in tendon thickness, stiffness, strength, and pain to see which approach better improves tendon and muscle function. Participants must be active (exercise at least 3 times per week) and have no prior knee surgeries or recent treatments like cortisone injections.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise training (eccentric training and heavy-slow resistance training)
- What this could lead to
- If successful, this could identify which type of exercise best improves tendon health and reduces pain in people with patellar tendinopathy.
- What could go wrong
- This is a small, early-stage study with only 30 participants, so results may not apply to everyone. Exercise programs require consistent effort and may not work for all individuals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Between 18 and 50 years of age * Pain at the inferior pole of the patella, longer than 3 months * Active lifestyle (sport/exercise minimum 3 times per week) * No previous injuries or surgeries on the affected leg Exclusion Criteria: * Corticoid injections in the last 6 months * Current intake of pain or non-steroidal anti-inflammatory drugs * Additional tendinopathy treatments in the last 6 months (i.e., physical therapy, shock-wave therapy, drug interventions, etc.) * Neuromuscular or cardiovascular associated diseases or conditions
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Graz
Graz, Styria, 8010, Austria
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