Exercise after nerve surgery: hope for arm recovery, but trial pulled
NCT ID NCT05859178
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study was designed to test whether a daily handgrip exercise program could speed up nerve regrowth and restore muscle and bone after brachial plexus injury surgery. It planned to enroll adults aged 18–60 with confirmed nerve damage. However, the trial was withdrawn before any participants were enrolled, so no data were collected.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- handgrip exercise
- What this could lead to
- If it worked, this could point toward a simple exercise program to improve recovery after nerve transfer surgery.
- What could go wrong
- The trial was withdrawn before any participants enrolled, so no results exist. Animal findings may not translate to humans.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Expected to start
-
Mar 2026
An estimate. Start dates often move.
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * adults age 18-60 * electrodiagnostically confirmed brachial plexus injury affecting the musculocutaneous nerve * able to consent for participation. Exclusion Criteria: • individuals with additional neurological or musculoskeletal conditions that would affect elbow and hand function
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Alberta
Edmonton, Alberta, T6G 2C9, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Ketamine infusion may ease chronic nerve pain in brachial plexus injuries