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Thigh muscle transplant may bring back elbow bending after nerve damage

NCT ID NCT07749313

Disease control Sponsor: Aswan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests a surgical technique to restore elbow bending in people who have lost this ability due to a brachial plexus injury that occurred more than a year earlier. Surgeons take a muscle from the thigh and move it to the arm, connecting its nerve to either the spinal accessory nerve or intercostal nerves. The study will measure how strong the new elbow flexion becomes and how well the arm functions overall.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Free functional gracilis muscle transfer, neurotized by either the spinal accessory nerve or intercostal nerves
What this could lead to
If successful, this procedure could offer a reliable way to restore meaningful elbow bending in people with long-standing brachial plexus injuries, improving arm function and daily independence.
What could go wrong
This is a small, single-arm study, and results may not apply broadly. Risks include flap loss, elbow flexion contracture, and variable recovery; not everyone may achieve functional strength.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

22 people

The number who actually took part.

Started

Jan 2024

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * More than 12 months after injury Exclusion Criteria: * younger than 4 years * older than 50

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Conditions

The condition(s) this trial relates to.

brachial plexus neuropathy brachial plexus neuropathy from injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brachial plexus palsy

Contacts and locations

Locations

  • Aswan University Hospitals

    Aswān, Aswan Governorate, 32337, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.