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Walking your way to a better memory with epilepsy?

NCT ID NCT04959019

Symptom relief Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a 6-week exercise program could improve memory in 71 adults with idiopathic generalized epilepsy. Participants either exercised or did nothing extra, and researchers measured memory and brain changes. The goal was to see if exercise helps memory and if those benefits last after the program ends.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

71 people

The number who actually took part.

Started

Jul 2021

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * males and females * ages 18-65 years old * speaks English fluently * able to provide written informed consent * have no contraindications to 3-Telsa MRI * clinician-confirmed diagnosis of IGE (IGE includes epilepsy syndromes such as juvenile myoclonic epilepsy, juvenile absence epilepsy, childhood absence epilepsy, and generalized tonic-clonic seizures alone) * relatively healthy with no comorbid medical conditions besides epilepsy * normal pre-enrollment structural clinical MRI of the brain (if available) * having less than the American Heart Association recommendation of physical activity in adults (at least 30 min moderate-intensity aerobic activity at least 5 days/week (150 min total), or at least 25 min vigorous aerobic activity at least 3 days/week (75 min total) and moderate-/high-intensity muscle strengthening activity at least 2 days/week) Exclusion Criteria: * underlying degenerative or metabolic disorders * abnormal general or neurological examination * abnormal brain MRI * recent suicidal ideation in the last 3 months determined based on previous medical history * pregnant or positive pregnancy test result on the day of the research session * contraindication to an MRI scan at 3-Telsa * mental handicap (FSIQ\<80 if tested) or history of special education * concurrent participation in a different intervention study * diseased or enlarged heart or blood vessels determined based on previous medical history * high blood pressure that is not controlled by medications * meeting the American Heart Association recommendation of physical activity in adults * abnormal physical examination in which study physician determines subject should not participate in the exercise intervention

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Conditions

The condition(s) this trial relates to.

Epilepsy, Generalized generalized epilepsy idiopathic generalized epilepsy Memory Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Epilepsy, generalized Memory impairment

Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.