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Exercise program aims to keep HIV patients over 50 on their feet
NCT ID NCT06139497
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a 48-week exercise program can improve physical function and reduce disability in HIV-positive adults over 50 in Côte d'Ivoire. 180 participants will be split into three groups: supervised group exercise, home-based exercise with phone support, or health education only. The main goal is to see if exercise helps them perform better on a step-up test after 6 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- physical activity programme
- What this could lead to
- If it works, this could show that structured exercise helps older HIV patients stay mobile and independent.
- What could go wrong
- This is a small pilot study (180 people) with no blinding, so results may not be generalizable. Participants may struggle to stick with the home-based program.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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180 people
The number who actually took part.
- Started
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Oct 2023
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Eligibility criteria for the intervention : Inclusion criteria: * Age ≥50 years * Documented HIV infection. * Receiving antiretroviral therapy for ≥ 12 months. * Residing in the Abobo district (Côte d'Ivoire). * Presence of at least one functional limitation or disability criterion among the following: * Performance in the 6-minute walk test ≤ 300 m. * Handgrip strength ≤ 35 kg for men or ≤ 24 kg for women. * WHODAS score ≥ 10. * SPPB score between 4 and 9. * Signed informed consent. Exclusion criteria * Medical contraindication to physical activity. * Anticipated unavailability. * Severe functional limitation (SPPB ≤ 3). * Another health condition requiring priority care. Eligibility criteria for the formative research: Inclusion criteria: People living with HIV: * Age ≥40 years * Documented HIV infection. * Receiving antiretroviral therapy for ≥ 12 months. Controls: * Age ≥40 years * Negative HIV test within the last 12 months; * Living in Abobo area * Written consent to participate to the study Exclusion Criteria: Participants living with HIV: * HIV infection with HIV-2 type only * Any clinical symptoms suggesting an acute infection * Any life-threatening pathology in the short term or any pathology not allowing participation in the study Controls: * Any clinical symptoms suggesting an acute infection * Any life-threatening pathology in the short term or any pathology not allowing participation in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Médical Spécialisé El Rapha
Abidjan, Côte d’Ivoire
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Formation semi urbaine (FSU) d'Abobo Avocatier
Abidjan, Côte d’Ivoire
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