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Which exercise eases leg pain best? new study aims to find out

NCT ID NCT07248137

Knowledge-focused Sponsor: European University Miguel de Cervantes Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test 16 people with peripheral arterial disease (PAD) to see how different types of exercise—walking on a treadmill, traditional strength training, and circuit training—affect blood flow, oxygen levels, and leg pain. Participants will try each exercise type in random order, and researchers will measure changes in their blood and heart rate. The goal is to find which exercise works best to improve symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aerobic exercise, traditional strength exercise, circuit strength exercise
What this could lead to
If successful, this could help identify the best exercise type to improve walking ability and reduce leg pain in people with peripheral arterial disease.
What could go wrong
This is a very small, early-stage study with only 16 participants, so results may not apply to everyone. It measures short-term effects, not long-term benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 16 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be 18 years of age or older. * Patients diagnosed with peripheral arterial disease at grade IIa or IIb according to the Leriche-Fontaine classification. Exclusion Criteria: * Patients with dementia or cognitive impairment. * Patients with recent major surgery (≤12 months) or lower limb amputations. * Patients institutionalized in healthcare facilities. * Patients dependent on a wheelchair. * Patients with any other condition contraindicating participation in an exercise program.

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Conditions

The condition(s) this trial relates to.

intermittent vascular claudication peripheral arterial disease vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aerobic physical exercise Circuit strength exercise Control Traditional strength exercise

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.