Can a smart exercise routine boost quality of life for women with hypothyroidism?
NCT ID NCT06757712
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study compares two 12-week resistance training programs—nonlinear and linear periodization—to see which better improves quality of life in women with hypothyroidism. 75 women aged 35-45 with controlled hypothyroidism will participate. The goal is to find an exercise approach that helps with both physical and mental well-being.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise program (nonlinear or linear periodized resistance training)
- What this could lead to
- If successful, this could show that a specific type of exercise program improves quality of life and thyroid-related health markers in women with hypothyroidism.
- What could go wrong
- This is a small, early-stage study with only 75 participants, so results may not apply to everyone. It tests exercise, not a new drug, so any benefits are likely modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 75 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Oct 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be controlled hypothyroidism (TSH level within 0.5 - 4.5 mU/L) * Be ranged from 35 to 45 years * Female patients * Body Mass Index 30-34.9 kg/m2 . * triglyceride-glucose (TyG) index \> 4.5 Exclusion Criteria: * history of pulmonary disease * Patients with uncontrolled coronary or cerebrovascular disease * Those who underwent musculoskeletal surgery within the previous year * Recent history of lower and upper limb fracture , hip and shoulder dislocation. * Cognitive impaired patients * Patients with history of epilepsy * Patients who participating in any other exercise program
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Suez University
RECRUITINGSuez, Egypt
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