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Scientists track ewing sarcoma cases to learn what works best

NCT ID NCT04845893

Knowledge-focused Sponsor: Italian Sarcoma Group Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people under 50 with a type of bone cancer called Ewing sarcoma. Researchers will collect information about patients' health, treatments, and results over time. The goal is to learn more about the disease and how it is treated, not to test a new drug or therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2021

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with Ewing's sarcoma of the bone or with Ewing-like sarcoma (round cell sarcoma with fusion of the EWSR1 gene with others not of the Ewings' Tumor Sarcoma family, sarcoma with Capicua Transcriptional Repressor (CIC) rearrangement or sarcoma with BCL6 corepressor (BCOR) rearrangement

Ages

0 to 49 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Diagnosis of Ewing's sarcoma of the bone 2. Diagnosis of Ewing-like sarcoma (round cell sarcoma with fusion of the EWSR1 gene with others not of the ETS family, sarcoma with CIC rearrangement or sarcoma with BCOR rearrangement) 3. Diagnosis of extraosseous Ewing's sarcoma for patients 4. Age at diagnosis \<50 years 5. Assessment of the extent of the disease at onset in accordance with the European Society of Medical Oncology guidelines 6. Patients or parents oe guardians of minors who have given their written informed consent to participate in the study Exclusion Criteria: 1\. Presence of comorbid factors who can compromise the compliance of the treatment plan or the evaluation of the outcomes, including but not limited to organ pathologies that contraindicate the use of chemotherapy and psychological or social conditions that do not allow for adequate compliance treatment or adequate follow-up

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Conditions

The condition(s) this trial relates to.

Ewing sarcoma Ewing sarcoma of bone extraskeletal Ewing sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ewing sarcoma of bone

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    19 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A.O. Universitaria Meyer

    RECRUITING

    Florence, 50139, Italy

  • A.O. Universitaria Policlinico S. Orsola Malpighi di Bologna

    RECRUITING

    Bologna, 40138, Italy

  • ARNAS P. O. "Civico e Benfratelli"

    RECRUITING

    Palermo, 90127, Italy

  • Azienda Ospedaliera Santobono Pausilipon

    NOT_YET_RECRUITING

    Naples, Italy

  • Azienda Ospedaliera Universitaria di Parma

    RECRUITING

    Parma, Italy

  • Azienda Ospedaliera di Padova

    RECRUITING

    Padova, Italy

  • Azienda Ospedaliero-Universitaria Pisana

    RECRUITING

    Pisa, 56126, Italy

  • Azienda ospedaliero universitaria consorziale policlinico - bari

    RECRUITING

    Bari, 70124, Italy

  • Centro di Riferimento Oncologico - Unit of Medical Oncology

    RECRUITING

    Aviano, Pordenone, 33081, Italy

  • FONDAZIONE IRCCS Istituto Nazionale dei Tumori

    RECRUITING

    Milan, Italy

  • FONDAZIONE IRCCS Istituto Nazionale dei Tumori

    RECRUITING

    Milan, Italy

  • I.R.C.C. - Unit of Medical Oncology

    RECRUITING

    Candiolo, Torino, 10060, Italy

  • IRCCS materno infantile Burlo Garofolo

    RECRUITING

    Trieste, 34137, Italy

  • Istituto Clinico Humanitas

    RECRUITING

    Rozzano, MI, 20089, Italy

  • Istituto Giannina Gaslini

    RECRUITING

    Genova, Italy

  • Istituto Regina Elena - IFO

    RECRUITING

    Rome, 00100, Italy

  • Istituto ortopedico Rizzoli

    RECRUITING

    Bologna, Italy

  • Ospedale Infantile Regina Margherita - Unit of Paediatric Oncoematology

    RECRUITING

    Torino, 10126, Italy

  • Ospedale Pediatrico Bambin Gesu'

    NOT_YET_RECRUITING

    Roma, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.