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New heart valve device offers hope for leaky valve patients

NCT ID NCT04221490

First seen Jan 09, 2026 · Last updated May 21, 2026 · Updated 17 times

Summary

This study tests a new device called EVOQUE to replace the tricuspid valve in people with a leaky heart valve that causes symptoms despite medication. About 228 participants will get the device to see if it safely reduces the leak and improves their condition. The goal is to control the disease and ease symptoms, not to cure it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor Heart Hopsital Plano

    Plano, Texas, 75093, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • CHU Bordeaux, Hôpital Cardiologique Haut Lévêque

    Pessac, 33600, France

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Clinique Pasteur

    Toulouse, 31076, France

  • Columbia University Irving Medical Center / NYPH

    New York, New York, 10032, United States

  • Emory University

    Atlanta, Georgia, 30308, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • InselSpital University Hospital Bern

    Bern, 3010, Switzerland

  • Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval (IUCPQ-ULaval)

    Québec, G1V 4G5, Canada

  • Massachusetts General Hospital Boston

    Boston, Massachusetts, 02114, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Piedmont Heart Institute

    Atlanta, Georgia, 30309, United States

  • St. Michael's Hospital

    Toronto, Ontario, M5B 1W8, Canada

  • St. Paul's Hospital Vancouver

    Vancouver, British Columbia, V6Z1Y6, Canada

  • Stanford University

    Stanford, California, 94305, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.