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Spine surgery pain relief without opioids?

NCT ID NCT07346599

Symptom relief Sponsor: Kutahya City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested whether a nerve block called an erector spinae plane (ESP) block can reduce pain after lumbar spine surgery. 102 adults were randomly assigned to receive either the ESP block or standard pain treatment. Researchers measured pain scores, opioid use, and how soon patients could get out of bed.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bilateral lumbar erector spinae plane (ESP) block
What this could lead to
If effective, this nerve block could offer a way to manage pain after spine surgery with fewer opioids and faster recovery.
What could go wrong
This is a single-center, completed trial with 102 participants, so results may not apply widely. The block may not reduce pain significantly or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

102 people

The number who actually took part.

Started

Sep 2021

Finished

May 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 and over, 80 and under * American Society of Anesthesiologists Patient Classification Score (ASA) between I and Ⅲ * Patients who can cooperate and give consent * No chronic analgesic or opioid use * No mental or psychiatric disorders * No alcohol or illicit drug use * Patients scheduled for elective spinal surgery Exclusion Criteria: * -Patients who withdrew from participation at any time during the study * Foreign nationals who could not be contacted * Patients under 18 and over 80 * Patients with an ASA score of Ⅳ or higher * Patients scheduled for emergency surgery * Pregnant women and breastfeeding mothers * Bleeding diathesis * Drug allergy * Anticoagulant use * Local/systemic infection * Serious arrhythmia

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nerve block Postoperative pain Randomised clinical trial

Contacts and locations

Locations

  • Afyonkarahisar Health Sciences University Hospital

    Afyonkarahisar, Merkez, 03000, Turkey (Türkiye)

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