Spine surgery pain relief without opioids?

NCT ID NCT07346599

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested whether a nerve block called an erector spinae plane (ESP) block can reduce pain after lumbar spine surgery. 102 adults were randomly assigned to receive either the ESP block or standard pain treatment. Researchers measured pain scores, opioid use, and how soon patients could get out of bed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bilateral lumbar erector spinae plane (ESP) block
What this could lead to
If effective, this nerve block could offer a way to manage pain after spine surgery with fewer opioids and faster recovery.
What could go wrong
This is a single-center, completed trial with 102 participants, so results may not apply widely. The block may not reduce pain significantly or could have side effects.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Afyonkarahisar Health Sciences University Hospital

    Afyonkarahisar, Merkez, 03000, Turkey (Türkiye)

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