Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a single injection numb the chest or belly? a nerve block under the microscope

NCT ID NCT04401007

Knowledge-focused Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This study tests a newer nerve block technique called the erector spinae plane (ESP) block, which involves injecting local anesthetic near the spine to numb the chest or abdominal wall. Healthy volunteers will receive the block with two different doses of lidocaine on separate visits to see how long and how completely it blocks sensation. The goal is to understand how well the block works and whether the dose affects its coverage, which could improve pain management after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Erector spinae plane (ESP) block with lidocaine and epinephrine
What this could lead to
If successful, this could help refine the ESP block technique, leading to more consistent and effective pain relief after surgery.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to patients. The block may not provide consistent coverage, and there are risks like infection or nerve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

Jul 2021

Finished

Nov 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ASA 1 (normal healthy) volunteers * 18 - 50 years of age * 60- 100 kg weight * English speaking * female volunteers of childbearing potential will be required to provide a negative pregnancy test before being allowed to participate, females of child bearing potential must be willing to use medically acceptable birth control methods for a minimum of 2 weeks following the nerve block. Exclusion Criteria: * weight \< 60 kg (limited by the maximum lidocaine dose 7 mg/kg) * medical disorders (including bleeding disorders) * any recreational drug use * allergy to local anesthetic (lidocaine, bupivacaine, ropivacaine) * contraindication to regional anesthetic block * inability to provide informed consent * baseline abnormality of chest, abdominal and back sensation * pregnancy / breast feeding * individuals with mental health disorders (for example bipolar disorder or depression).

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Pain management are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain management

Contacts and locations

Locations

  • University Health Network

    Toronto, Ontario, M5T 2S8, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.