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Lung cancer drug combo tested in Mid-Stage trial

NCT ID NCT01708954

Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 10, 2026 · Updated 3 times

Summary

This phase 2 trial tests two drugs, erlotinib and cabozantinib, given alone or together in 125 patients with advanced non-small cell lung cancer that does not have a common EGFR mutation. The goal is to see if the combination works better than either drug alone to slow cancer growth. Participants must have already had at least one prior treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
erlotinib and cabozantinib (drugs)
What this could lead to
If successful, this could point toward a new treatment option for advanced lung cancer patients who have not responded to prior therapies.
What could go wrong
This is a mid-stage trial with only 125 participants, so results may not apply to everyone. The drugs can cause side effects like rash, diarrhea, and fatigue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

125 people

The number who actually took part.

Started

Feb 2013

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Criteria: * Tumor with a sensitizing mutation in epidermal growth factor receptor (EGFR), defined as follows: * EGFR mutation testing of tumor has been performed and did not demonstrate an EGFR tyrosine kinase inhibitor sensitizing mutation; at minimum, testing for EGFR exon 19 deletion and exon 21 L858R mutations must have been included; OR * EGFR mutation testing has been attempted and is inconclusive (for example, due to lack of sufficient deoxyribonucleic acid \[DNA\] yield); OR * EGFR mutation status is unknown but tumor is positive for at least one alternative driver mutation, i.e: Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation, v-raf murine sarcoma viral oncogene homolog B (BRAF) mutation, human epidermal growth factor receptor 2 (HER2) mutation, ret proto-oncogene (RET) rearrangement/fusion, or one not listed following approval by the study chair prior to registration Inclusion Criteria: * INCLUSION CRITERIA STEP 1: * Cytologically or histologically confirmed non-small cell lung carcinoma (NSCLC) * Predominant non-squamous histology (patients with NSCLC not otherwise specified \[NOS\] are eligible); mixed tumors will be categorized by the predominant cell type; if small cell elements are present the patient is ineligible * Stage IV disease (includes M1a, M1b, or recurrent disease), according to the 7th edition of the lung cancer TNM classification system * Patients must have measurable disease as defined by Response Evaluation Criteria in Solid Tumors (RECIST) version (v) 1.1 criteria; baseline measurements and evaluation of all sites of disease must be obtained within 4 weeks prior to registration * Prior to registration, the investigator/site must confirm that sufficient pathology material representative of patient's cancer is available for submission for MET immunohistochemical (IHC) testing * Patients must have received one or two lines of prior chemotherapy (first line platinum-doublet based chemotherapy plus switch maintenance chemotherapy counts as one line of therapy); prior adjuvant chemotherapy for early stage disease does not count as one line of therapy if 12 months or greater elapsed between completion of adjuvant therapy and initiation of first-line systemic therapy; if less than 12 months elapsed, adjuvant chemotherapy counts as one line of therapy * Any prior chemotherapy (based on administration schedule) must have been completed in greater than or equal to the time frames specified in the protocol * Patients must have discontinued treatment with any other type of investigational agent \>= 4 weeks prior to registration * Patients must have recovered to baseline or Common Terminology Criteria for Adverse Events (CTCAE) v 4.0 =\< grade 1 from toxicity due to all prior therapies except alopecia and other non-clinically significant adverse events (AEs) * Patients with no known brain metastasis at baseline must have baseline brain imaging within 12 weeks prior to study registration not demonstrating brain metastases; patients with brain metastases at baseline must have baseline brain imagining within 4 weeks prior to study registration and meet all of the specific criteria for brain mets listed in the protocol * Radiation related toxicities must have resolved to =\< grade 1 prior to registration * Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status between 0-2 * Patients must have an anticipated life expectancy greater than 3 months * Acceptable bone marrow, renal and hepatic function within 2 weeks prior to registration as defined in the protocol * Patients must have corrected QT interval calculated by the Fridericia formula (QTcF) =\< 500 ms within 28 days before registration * Patients must be able to swallow tablets * INCLUSION CRITERIA STEP 2: * Patients must have met all eligibility requirements for Step 1 at time of registration to Step 1 to be eligible for Step 2 * Patients must have radiographic progressive disease per RECIST v1.1 criteria after \>= 2 courses of therapy on Arm A or Arm B * Patients must be registered to Step 2 within 4 weeks of the last dose of treatment administration from Step 1 * Patients must have an ECOG performance status between 0-2 * Patients must have recovered to baseline (pre-Step 1) or CTCAE version 4.0 \<= grade 1 from toxicity due to all prior therapies except alopecia and other non-clinically significant AEs Exclusion Criteria: * EXCLUSION CRITERIA STEP 1: * Patients without sufficient pathology material representative of the patient's cancer (tumor block or 10 unstained slides) * Prior erlotinib, other EGFR tyrosine kinase inhibitor therapy, vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor therapy, Met tyrosine kinase inhibitor therapy, or Met monoclonal antibody (MetMAb); prior antibody therapy such as bevacizumab or cetuximab is allowed with a washout period depending on dosing interval and investigational nature * Prior radiation therapy to the thoracic cavity, abdomen, or pelvis within 3 months prior to registration, to bone or brain metastasis within 14 days prior to registration, or to any other site within 28 days prior to registration * History of the following: Clinically-significant gastrointestinal (GI) bleeding within 6 months prior to registration; Hemoptysis of \>= 0.5 teaspoon (2.5 mL) of red blood within 3 months prior to registration; Any other signs indicative of pulmonary hemorrhage within 3 months prior to registration * Radiographic or other evidence of the following within 28 days prior to registration: • Tumor invading the GI tract (esophagus, stomach, small or large bowel, rectum or anus), or any evidence of endotracheal or endobronchial tumor; Cavitating pulmonary lesion(s); Tumor in contact with, invading or encasing any major blood vessels * Psychiatric illness/social situations that would limit compliance with study requirements * History of major thrombotic events (deep vein thrombosis \[DVT\] or pulmonary embolism \[PE\]) within 6 months prior to registration * Concomitant treatment, in therapeutic doses, with anticoagulants such as warfarin or warfarin-related agents, heparin, low molecular weight heparin (LMWH), thrombin or Factor Xa inhibitors, or antiplatelet agents (e.g., clopidogrel). (low dose aspirin \[=\< 81 mg/day\] and prophylactic LMWH are permitted) * Concomitant treatment of strong cytochrome P450 3A4 (CYP3A4) inducers (e.g., dexamethasone, phenytoin, carbamazepine, rifampin, rifabutin, rifapentine, phenobarbital, and St. John's wort) * Cardiovascular disorders including: Congestive heart failure (CHF): New York Heart Association (NYHA) class III (moderate) or class IV (severe) at the time of screening; * Concurrent uncontrolled hypertension; Any history of congenital long QT syndrome; Any of the following within 6 months prior to registration: * Unstable angina pectoris * Clinically-significant cardiac arrhythmias * Stroke (including transient ischemic attack \[TIA\], or other ischemic event) * Myocardial infarction * GI disorders particularly those associated with a high risk of perforation or fistula formation specified in the protocol * Other disorders associated with a high risk of fistula formation including percutaneous endoscopic gastrostomy (PEG) tube placement within 3 months prior to registration * Uncontrolled, significant, intercurrent or recent illness * Prior malignancy within 2 years prior to registration which required systemic treatment or is currently active * Pregnant or breast-feeding * Patients with known human immunodeficiency virus (HIV) disease taking antiretroviral therapy * Known chronic active hepatitis B * EXCLUSION CRITERIA (STEP 2): * Intervening anticancer treatment or major surgical procedure(s) between Step 1 and Step 2, except palliative radiation to the bone finishing \>= 2 weeks prior to registration to Step 2 * Central nervous system (CNS) progression; patients with stable CNS disease are allowed * Intercurrent illness or disease complication that the investigator believes would limit the ability to safely tolerate the combination of erlotinib and cabozantinib

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Recurrent lung non-small cell carcinoma Stage IV lung non-small cell cancer ajcc V7

Contacts and locations

Locations

  • AMG Libertyville - Oncology

    Libertyville, Illinois, 60048, United States

  • Abbott-Northwestern Hospital

    Minneapolis, Minnesota, 55407, United States

  • Adena Regional Medical Center

    Chillicothe, Ohio, 45601, United States

  • AdventHealth Littleton

    Littleton, Colorado, 80122, United States

  • AdventHealth Parker

    Parker, Colorado, 80138, United States

  • AdventHealth Porter

    Denver, Colorado, 80210, United States

  • Alegent Health Bergan Mercy Medical Center

    Omaha, Nebraska, 68124, United States

  • Alegent Health Immanuel Medical Center

    Omaha, Nebraska, 68122, United States

  • Alegent Health Lakeside Hospital

    Omaha, Nebraska, 68130, United States

  • Allegiance Health

    Jackson, Michigan, 49201, United States

  • Ascension Via Christi Hospitals Wichita

    Wichita, Kansas, 67214, United States

  • Aspirus Cancer Care - Stevens Point

    Stevens Point, Wisconsin, 54481, United States

  • Aspirus Cancer Care - Wisconsin Rapids

    Wisconsin Rapids, Wisconsin, 54494, United States

  • Aspirus Cancer Care-Rhinelander-James Beck Cancer Center

    Rhinelander, Wisconsin, 54501, United States

  • Associates In Womens Health

    Wichita, Kansas, 67208, United States

  • Atlanta VA Medical Center

    Decatur, Georgia, 30033, United States

  • Atrium Health Navicent

    Macon, Georgia, 31201, United States

  • Banner North Colorado Medical Center

    Greeley, Colorado, 80631, United States

  • Banner North Colorado Medical Center - Loveland Campus

    Loveland, Colorado, 80539, United States

  • Bay Area Medical Center

    Marinette, Wisconsin, 54143, United States

  • Beacon Kalamazoo

    Kalamazoo, Michigan, 49048, United States

  • Beebe Health Campus

    Rehoboth Beach, Delaware, 19971, United States

  • Beebe Medical Center

    Lewes, Delaware, 19958, United States

  • Bixby Medical Center

    Adrian, Michigan, 49221, United States

  • Boulder Community Foothills Hospital

    Boulder, Colorado, 80303, United States

  • Bronson Methodist Hospital

    Kalamazoo, Michigan, 49007, United States

  • Bryn Mawr Hospital

    Bryn Mawr, Pennsylvania, 19010, United States

  • Cancer Care Specialists of Illinois - Decatur

    Decatur, Illinois, 62526, United States

  • Cancer Center of Kansas - Chanute

    Chanute, Kansas, 66720, United States

  • Cancer Center of Kansas - Dodge City

    Dodge City, Kansas, 67801, United States

  • Cancer Center of Kansas - El Dorado

    El Dorado, Kansas, 67042, United States

  • Cancer Center of Kansas - Fort Scott

    Fort Scott, Kansas, 66701, United States

  • Cancer Center of Kansas - McPherson

    McPherson, Kansas, 67460, United States

  • Cancer Center of Kansas - Newton

    Newton, Kansas, 67114, United States

  • Cancer Center of Kansas - Parsons

    Parsons, Kansas, 67357, United States

  • Cancer Center of Kansas - Pratt

    Pratt, Kansas, 67124, United States

  • Cancer Center of Kansas - Salina

    Salina, Kansas, 67401, United States

  • Cancer Center of Kansas - Wellington

    Wellington, Kansas, 67152, United States

  • Cancer Center of Kansas - Wichita

    Wichita, Kansas, 67214, United States

  • Cancer Center of Kansas - Winfield

    Winfield, Kansas, 67156, United States

  • Cancer Center of Kansas-Independence

    Independence, Kansas, 67301, United States

  • Cancer Center of Kansas-Kingman

    Kingman, Kansas, 67068, United States

  • Cancer Center of Kansas-Liberal

    Liberal, Kansas, 67905, United States

  • Cancer Center of Kansas-Manhattan

    Manhattan, Kansas, 66502, United States

  • Cancer Center of Kansas-Wichita Medical Arts Tower

    Wichita, Kansas, 67208, United States

  • Cancer Center of Western Wisconsin

    New Richmond, Wisconsin, 54017, United States

  • Cancer Therapy and Integrative Medicine

    Las Vegas, Nevada, 89121, United States

  • Cancer and Blood Specialists-Henderson

    Henderson, Nevada, 89052, United States

  • Cancer and Blood Specialists-Shadow

    Las Vegas, Nevada, 89106, United States

  • Cancer and Blood Specialists-Tenaya

    Las Vegas, Nevada, 89128, United States

  • Carle Cancer Center

    Urbana, Illinois, 61801, United States

  • Carle Cancer Institute Normal

    Normal, Illinois, 61761, United States

  • Carle Physician Group-Effingham

    Effingham, Illinois, 62401, United States

  • Carle Physician Group-Mattoon/Charleston

    Mattoon, Illinois, 61938, United States

  • Carle at The Riverfront

    Danville, Illinois, 61832, United States

  • Case Western Reserve University

    Cleveland, Ohio, 44106, United States

  • Centralia Oncology Clinic

    Centralia, Illinois, 62801, United States

  • Christiana Care - Union Hospital

    Elkton, Maryland, 21921, United States

  • Christiana Care Health System-Christiana Hospital

    Newark, Delaware, 19718, United States

  • Christiana Care Health System-Wilmington Hospital

    Wilmington, Delaware, 19801, United States

  • Cleveland Clinic Mercy Hospital

    Canton, Ohio, 44708, United States

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • Columbus NCI Community Oncology Research Program

    Columbus, Ohio, 43215, United States

  • Columbus Oncology and Hematology Associates Inc

    Columbus, Ohio, 43214, United States

  • CommonSpirit Saint Anthony Hospital Cancer Center

    Lakewood, Colorado, 80228, United States

  • Community Hospital of Monterey Peninsula

    Monterey, California, 93940, United States

  • Community Howard Regional Health

    Kokomo, Indiana, 46904, United States

  • Comprehensive Cancer Centers of Nevada

    Las Vegas, Nevada, 89148, United States

  • Comprehensive Cancer Centers of Nevada - Central Valley

    Las Vegas, Nevada, 89169, United States

  • Comprehensive Cancer Centers of Nevada - Henderson

    Henderson, Nevada, 89052, United States

  • Comprehensive Cancer Centers of Nevada - Northwest

    Las Vegas, Nevada, 89128, United States

  • Comprehensive Cancer Centers of Nevada-Southeast Henderson

    Henderson, Nevada, 89074, United States

  • Comprehensive Cancer Centers of Nevada-Summerlin

    Las Vegas, Nevada, 89144, United States

  • Constantinou, Costas L MD (UIA Investigator)

    Bettendorf, Iowa, 52722, United States

  • Cooper Hospital University Medical Center

    Camden, New Jersey, 08103, United States

  • Corewell Health Dearborn Hospital

    Dearborn, Michigan, 48124, United States

  • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center

    Saint Joseph, Michigan, 49085, United States

  • Corewell Health Lakeland Hospitals - Saint Joseph Hospital

    Saint Joseph, Michigan, 49085, United States

  • Crossroads Cancer Center

    Effingham, Illinois, 62401, United States

  • Decatur Memorial Hospital

    Decatur, Illinois, 62526, United States

  • Delaware Clinical and Laboratory Physicians PA

    Newark, Delaware, 19713, United States

  • Delaware Health Center-Grady Cancer Center

    Delaware, Ohio, 43015, United States

  • Delaware Radiation Oncology

    Delaware, Ohio, 43015, United States

  • Dell Seton Medical Center at The University of Texas

    Austin, Texas, 78701, United States

  • Dickstein Cancer Treatment Center

    White Plains, New York, 10601, United States

  • Doctors Hospital

    Columbus, Ohio, 43228, United States

  • Doylestown Hospital

    Doylestown, Pennsylvania, 18901, United States

  • Einstein Medical Center Philadelphia

    Philadelphia, Pennsylvania, 19141, United States

  • Eisenhower Medical Center

    Rancho Mirage, California, 92270, United States

  • Elkhart Clinic

    Elkhart, Indiana, 46514-2098, United States

  • Elkhart General Hospital

    Elkhart, Indiana, 46515, United States

  • Emory Saint Joseph's Hospital

    Atlanta, Georgia, 30342, United States

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Fairfield Medical Center

    Lancaster, Ohio, 43130, United States

  • Fairview Ridges Hospital

    Burnsville, Minnesota, 55337, United States

  • Fairview Southdale Hospital

    Edina, Minnesota, 55435, United States

  • Franciscan Saint Anthony Health-Michigan City

    Michigan City, Indiana, 46360, United States

  • Fredericksburg Oncology Inc

    Fredericksburg, Virginia, 22401, United States

  • Fulton County Health Center

    Wauseon, Ohio, 43567, United States

  • Garneau, Stewart C MD (UIA Investigator)

    Moline, Illinois, 61265, United States

  • Geisinger Cancer Services-Pottsville

    Pottsville, Pennsylvania, 17901, United States

  • Geisinger Medical Center

    Danville, Pennsylvania, 17822, United States

  • Geisinger Medical Center-Cancer Center Hazleton

    Hazleton, Pennsylvania, 18201, United States

  • Geisinger Medical Group

    State College, Pennsylvania, 16801, United States

  • Geisinger Medical Oncology-Lewisburg

    Lewisburg, Pennsylvania, 17837, United States

  • Geisinger Wyoming Valley/Henry Cancer Center

    Wilkes-Barre, Pennsylvania, 18711, United States

  • Genesis Healthcare System Cancer Care Center

    Zanesville, Ohio, 43701, United States

  • Genesys Hurley Cancer Institute

    Flint, Michigan, 48503, United States

  • Grady Memorial Hospital

    Delaware, Ohio, 43015, United States

  • Grant Medical Center

    Columbus, Ohio, 43215, United States

  • Greater Baltimore Medical Center

    Baltimore, Maryland, 21204, United States

  • Green Bay Oncology at Saint Vincent Hospital

    Green Bay, Wisconsin, 54301-3526, United States

  • Guthrie Medical Group PC-Robert Packer Hospital

    Sayre, Pennsylvania, 18840, United States

  • HSHS Sacred Heart Hospital

    Eau Claire, Wisconsin, 54701, United States

  • HSHS Saint Nicholas Hospital

    Sheboygan, Wisconsin, 53081, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

    Las Vegas, Nevada, 89149, United States

  • HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

    Las Vegas, Nevada, 89109, United States

  • HealthCare Partners Medical Group Oncology/Hematology-San Martin

    Las Vegas, Nevada, 89113, United States

  • HealthCare Partners Medical Group Oncology/Hematology-Tenaya

    Las Vegas, Nevada, 89128, United States

  • Heartland Cancer Research NCORP

    Decatur, Illinois, 62526, United States

  • Helen F Graham Cancer Center

    Newark, Delaware, 19713, United States

  • Hematology Oncology Associates of Illinois - Skokie

    Skokie, Illinois, 60076, United States

  • Hematology Oncology Associates of Illinois-Highland Park

    Highland Park, Illinois, 60035, United States

  • Hennepin County Medical Center

    Minneapolis, Minnesota, 55415, United States

  • Henry Ford Health Saint John Hospital

    Detroit, Michigan, 48236, United States

  • Henry Ford Health Warren Hospital

    Warren, Michigan, 48093, United States

  • Hickman Cancer Center

    Adrian, Michigan, 49221, United States

  • Holy Family Memorial Hospital

    Manitowoc, Wisconsin, 54221, United States

  • Hurley Medical Center

    Flint, Michigan, 48503, United States

  • Hutchinson Area Health Care

    Hutchinson, Minnesota, 55350, United States

  • IU Health Ball Memorial Hospital

    Muncie, Indiana, 47303, United States

  • IU Health Bloomington

    Bloomington, Indiana, 47408, United States

  • IU Health Central Indiana Cancer Centers-East

    Indianapolis, Indiana, 46219, United States

  • IU Health La Porte Hospital

    La Porte, Indiana, 46350, United States

  • Illinois Cancer Specialists-Niles

    Niles, Illinois, 60714, United States

  • Illinois CancerCare-Bloomington

    Bloomington, Illinois, 61704, United States

  • Illinois CancerCare-Canton

    Canton, Illinois, 61520, United States

  • Illinois CancerCare-Carthage

    Carthage, Illinois, 62321, United States

  • Illinois CancerCare-Eureka

    Eureka, Illinois, 61530, United States

  • Illinois CancerCare-Galesburg

    Galesburg, Illinois, 61401, United States

  • Illinois CancerCare-Kewanee Clinic

    Kewanee, Illinois, 61443, United States

  • Illinois CancerCare-Macomb

    Macomb, Illinois, 61455, United States

  • Illinois CancerCare-Monmouth

    Monmouth, Illinois, 61462, United States

  • Illinois CancerCare-Ottawa Clinic

    Ottawa, Illinois, 61350, United States

  • Illinois CancerCare-Pekin

    Pekin, Illinois, 61554, United States

  • Illinois CancerCare-Peoria

    Peoria, Illinois, 61615, United States

  • Illinois CancerCare-Peru

    Peru, Illinois, 61354, United States

  • Illinois CancerCare-Princeton

    Princeton, Illinois, 61356, United States

  • Illinois Valley Hospital

    Peru, Illinois, 61354, United States

  • Indiana University/Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Ingalls Memorial Hospital

    Harvey, Illinois, 60426, United States

  • Inspira Medical Center Vineland

    Vineland, New Jersey, 08360, United States

  • Intermountain Health Lutheran Hospital

    Wheat Ridge, Colorado, 80401, United States

  • Iowa Lutheran Hospital

    Des Moines, Iowa, 50316, United States

  • Iowa Methodist Medical Center

    Des Moines, Iowa, 50309, United States

  • Iowa-Wide Oncology Research Coalition NCORP

    Des Moines, Iowa, 50309, United States

  • Knox Community Hospital

    Mount Vernon, Ohio, 43050, United States

  • Lake Huron Medical Center

    Port Huron, Michigan, 48060, United States

  • Lakeview Hospital

    Stillwater, Minnesota, 55082, United States

  • Lancaster General Hospital

    Lancaster, Pennsylvania, 17602, United States

  • Lankenau Medical Center

    Wynnewood, Pennsylvania, 19096, United States

  • Las Vegas Cancer Center-Henderson

    Henderson, Nevada, 89052, United States

  • Las Vegas Cancer Center-Medical Center

    Las Vegas, Nevada, 89148-2405, United States

  • Lawrence Memorial Hospital

    Lawrence, Kansas, 66044, United States

  • Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

    Savannah, Georgia, 31405, United States

  • Licking Memorial Hospital

    Newark, Ohio, 43055, United States

  • Lima Memorial Hospital

    Lima, Ohio, 45804, United States

  • Longmont United Hospital

    Longmont, Colorado, 80501, United States

  • Main Line Health NCORP

    Wynnewood, Pennsylvania, 19096, United States

  • Marietta Memorial Hospital

    Marietta, Ohio, 45750, United States

  • Marshfield Clinic - Wisconsin Rapids Center

    Wisconsin Rapids, Wisconsin, 54494, United States

  • Marshfield Clinic Cancer Center at Sacred Heart

    Eau Claire, Wisconsin, 54701, United States

  • Marshfield Clinic-Chippewa Center

    Chippewa Falls, Wisconsin, 54729, United States

  • Marshfield Clinic-Wausau Center

    Wausau, Wisconsin, 54401, United States

  • Marshfield Medical Center

    Marshfield, Wisconsin, 54449, United States

  • Marshfield Medical Center - Minocqua

    Minocqua, Wisconsin, 54548, United States

  • Marshfield Medical Center - Weston

    Weston, Wisconsin, 54476, United States

  • Marshfield Medical Center-Marshfield

    Marshfield, Wisconsin, 54449, United States

  • Marshfield Medical Center-Rice Lake

    Rice Lake, Wisconsin, 54868, United States

  • Mary Greeley Medical Center

    Ames, Iowa, 50010, United States

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • McFarland Clinic - Ames

    Ames, Iowa, 50010, United States

  • McFarland Clinic - Boone

    Boone, Iowa, 50036, United States

  • McFarland Clinic - Jefferson

    Jefferson, Iowa, 50129, United States

  • McFarland Clinic - Marshalltown

    Marshalltown, Iowa, 50158, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Medical Oncology Hematology Consultants PA

    Newark, Delaware, 19713, United States

  • Memorial Hospital of South Bend

    South Bend, Indiana, 46601, United States

  • Memorial Medical Center

    Modesto, California, 95355, United States

  • Memorial Medical Center-Las Cruces

    Las Cruces, New Mexico, 88011, United States

  • Mercy Cancer Center-West Lakes

    Clive, Iowa, 50325, United States

  • Mercy Health - Saint Anne Hospital

    Toledo, Ohio, 43623, United States

  • Mercy Health - Saint Vincent Hospital

    Toledo, Ohio, 43608, United States

  • Mercy Hospital

    Cedar Rapids, Iowa, 52403, United States

  • Mercy Hospital

    Coon Rapids, Minnesota, 55433, United States

  • Mercy Hospital of Tiffin

    Tiffin, Ohio, 44883, United States

  • Mercy Medical Center

    Durango, Colorado, 81301, United States

  • Mercy Medical Center - Des Moines

    Des Moines, Iowa, 50314, United States

  • Mercy Medical Center - North Iowa

    Mason City, Iowa, 50401, United States

  • Mercy Medical Center-Sioux City

    Sioux City, Iowa, 51102, United States

  • Mercy Medical Center-West Lakes

    West Des Moines, Iowa, 50266, United States

  • Mercy Memorial Hospital

    Monroe, Michigan, 48162, United States

  • Methodist Medical Center of Illinois

    Peoria, Illinois, 61636, United States

  • Metro Minnesota Community Oncology Research Consortium

    Saint Louis Park, Minnesota, 55416, United States

  • MetroHealth Medical Center

    Cleveland, Ohio, 44109, United States

  • Michiana Hematology Oncology PC-Elkhart

    Elkhart, Indiana, 46514, United States

  • Michiana Hematology Oncology PC-Mishawaka

    Mishawaka, Indiana, 46545, United States

  • Michiana Hematology Oncology PC-Plymouth

    Plymouth, Indiana, 46563, United States

  • Michiana Hematology Oncology PC-Westville

    Westville, Indiana, 46391, United States

  • Michigan Cancer Research Consortium NCORP

    Ann Arbor, Michigan, 48106, United States

  • Minnesota Oncology Hematology PA-Maplewood

    Maplewood, Minnesota, 55109, United States

  • Minnesota Oncology Hematology PA-Woodbury

    Woodbury, Minnesota, 55125, United States

  • Missouri Valley Cancer Consortium

    Omaha, Nebraska, 68106, United States

  • Monmouth Medical Center

    Long Branch, New Jersey, 07740, United States

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, 10467, United States

  • Montefiore Medical Center-Weiler Hospital

    The Bronx, New York, 10461, United States

  • Morristown Medical Center

    Morristown, New Jersey, 07960, United States

  • Mount Carmel Health Center West

    Columbus, Ohio, 43222, United States

  • Mountain Blue Cancer Care Center

    Golden, Colorado, 80401, United States

  • Mountain Blue Cancer Care Center - Swedish

    Englewood, Colorado, 80113, United States

  • MyMichigan Medical Center Saginaw

    Saginaw, Michigan, 48601, United States

  • Nebraska Cancer Research Center

    Lincoln, Nebraska, 68510, United States

  • Nevada Cancer Research Foundation NCORP

    Las Vegas, Nevada, 89120, United States

  • New Ulm Medical Center

    New Ulm, Minnesota, 56073, United States

  • Newark Radiation Oncology

    Newark, Ohio, 43055, United States

  • North Memorial Medical Health Center

    Robbinsdale, Minnesota, 55422, United States

  • NorthShore University HealthSystem-Evanston Hospital

    Evanston, Illinois, 60201, United States

  • NorthShore University HealthSystem-Glenbrook Hospital

    Glenview, Illinois, 60026, United States

  • NorthShore University HealthSystem-Highland Park Hospital

    Highland Park, Illinois, 60035, United States

  • Northern Indiana Cancer Research Consortium

    South Bend, Indiana, 46628, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • OSF Saint Francis Hospital and Medical Group

    Escanaba, Michigan, 49829, United States

  • OSF Saint Francis Medical Center

    Peoria, Illinois, 61637, United States

  • OSF Saint Francis Radiation Oncology at Pekin

    Pekin, Illinois, 61554, United States

  • OSF Saint Joseph Medical Center

    Bloomington, Illinois, 61701, United States

  • Ochsner Baptist Medical Center

    New Orleans, Louisiana, 70115, United States

  • Ochsner Health Center-Summa

    Baton Rouge, Louisiana, 70809, United States

  • Ochsner Medical Center Jefferson

    New Orleans, Louisiana, 70121, United States

  • Oncology Associates at Mercy Medical Center

    Cedar Rapids, Iowa, 52403, United States

  • Oncology Las Vegas - Henderson

    Henderson, Nevada, 89074, United States

  • Oncology Las Vegas - Tenaya

    Las Vegas, Nevada, 89128, United States

  • OptumCare Cancer Care at Fort Apache

    Las Vegas, Nevada, 89183, United States

  • Ottawa Regional Hospital and Healthcare Center

    Ottawa, Illinois, 61350, United States

  • Overlook Hospital

    Summit, New Jersey, 07902, United States

  • Paoli Memorial Hospital

    Paoli, Pennsylvania, 19301, United States

  • Park Nicollet Clinic - Saint Louis Park

    Saint Louis Park, Minnesota, 55416, United States

  • Penn State Milton S Hershey Medical Center

    Hershey, Pennsylvania, 17033-0850, United States

  • Penrose-Saint Francis Healthcare

    Colorado Springs, Colorado, 80907, United States

  • Porubcin, Michael MD (UIA Investigator)

    Moline, Illinois, 61265, United States

  • Presbyterian - Saint Lukes Medical Center - Health One

    Denver, Colorado, 80218, United States

  • Presence Saint Mary's Hospital

    Kankakee, Illinois, 60901, United States

  • ProHealth Oconomowoc Memorial Hospital

    Oconomowoc, Wisconsin, 53066, United States

  • ProHealth Waukesha Memorial Hospital

    Waukesha, Wisconsin, 53188, United States

  • ProMedica Flower Hospital

    Sylvania, Ohio, 43560, United States

  • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital

    Toledo, Ohio, 43606, United States

  • Proctor Hospital

    Peoria, Illinois, 61614, United States

  • Radiation Oncology Centers of Nevada Central

    Las Vegas, Nevada, 89106, United States

  • Radiation Oncology Centers of Nevada Southeast

    Las Vegas, Nevada, 89119, United States

  • Regions Hospital

    Saint Paul, Minnesota, 55101, United States

  • Rice Memorial Hospital

    Willmar, Minnesota, 56201, United States

  • Ridgeview Medical Center

    Waconia, Minnesota, 55387, United States

  • Riverside Methodist Hospital

    Columbus, Ohio, 43214, United States

  • Rocky Mountain Cancer Centers - Pueblo

    Pueblo, Colorado, 81008, United States

  • Rocky Mountain Cancer Centers-Boulder

    Boulder, Colorado, 80304, United States

  • Rocky Mountain Cancer Centers-Greenwood Village

    Greenwood Village, Colorado, 80111, United States

  • Rocky Mountain Cancer Centers-Lakewood

    Lakewood, Colorado, 80228, United States

  • Rocky Mountain Cancer Centers-Longmont

    Longmont, Colorado, 80501, United States

  • Rocky Mountain Cancer Centers-Midtown

    Denver, Colorado, 80218, United States

  • Rocky Mountain Cancer Centers-Parker

    Parker, Colorado, 80138, United States

  • Rocky Mountain Cancer Centers-Penrose

    Colorado Springs, Colorado, 80907, United States

  • Rocky Mountain Cancer Centers-Rose

    Denver, Colorado, 80220, United States

  • Rocky Mountain Cancer Centers-Sky Ridge

    Lone Tree, Colorado, 80124, United States

  • Rose Medical Center

    Denver, Colorado, 80220, United States

  • Rush-Copley Healthcare Center

    Yorkville, Illinois, 60560, United States

  • Rush-Copley Medical Center

    Aurora, Illinois, 60504, United States

  • Rutgers New Jersey Medical School

    Newark, New Jersey, 07101, United States

  • SSM Health Dean Medical Group - South Madison Campus

    Madison, Wisconsin, 53715, United States

  • Saint Alphonsus Cancer Care Center-Boise

    Boise, Idaho, 83706, United States

  • Saint Ann's Hospital

    Westerville, Ohio, 43081, United States

  • Saint Charles Hospital

    Oregon, Ohio, 43616, United States

  • Saint Francis Medical Center

    Cape Girardeau, Missouri, 63703, United States

  • Saint Francis Regional Medical Center

    Shakopee, Minnesota, 55379, United States

  • Saint John's Hospital - Healtheast

    Maplewood, Minnesota, 55109, United States

  • Saint Joseph Hospital - Cancer Centers of Colorado

    Denver, Colorado, 80218, United States

  • Saint Joseph Regional Medical Center-Mishawaka

    Mishawaka, Indiana, 46545, United States

  • Saint Luke's Regional Medical Center

    Sioux City, Iowa, 51104, United States

  • Saint Mary Corwin Medical Center

    Pueblo, Colorado, 81004, United States

  • Saint Mary's Hospital

    Rhinelander, Wisconsin, 54501, United States

  • Saint Rita's Medical Center

    Lima, Ohio, 45801, United States

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay, Wisconsin, 54301, United States

  • Saint Vincent Hospital Cancer Center at Oconto Falls

    Oconto Falls, Wisconsin, 54154, United States

  • Saint Vincent Hospital Cancer Center at Saint Mary's

    Green Bay, Wisconsin, 54303, United States

  • Sanford Broadway Medical Center

    Fargo, North Dakota, 58122, United States

  • Sanford Cancer Center Oncology Clinic

    Sioux Falls, South Dakota, 57104, United States

  • Sanford Joe Lueken Cancer Center

    Bemidji, Minnesota, 56601, United States

  • Sanford Roger Maris Cancer Center

    Fargo, North Dakota, 58122, United States

  • Sanford USD Medical Center - Sioux Falls

    Sioux Falls, South Dakota, 57117-5134, United States

  • Siouxland Regional Cancer Center

    Sioux City, Iowa, 51101, United States

  • Sky Ridge Medical Center

    Lone Tree, Colorado, 80124, United States

  • Smilow Cancer Hospital Care Center at Saint Francis

    Hartford, Connecticut, 06105, United States

  • South Bend Clinic

    South Bend, Indiana, 46617, United States

  • Southern Ohio Medical Center

    Portsmouth, Ohio, 45662, United States

  • Spector, David MD (UIA Investigator)

    Moline, Illinois, 61265, United States

  • Springfield Memorial Hospital

    Springfield, Illinois, 62781, United States

  • Springfield Regional Medical Center

    Springfield, Ohio, 45504, United States

  • Stanford Cancer Institute Palo Alto

    Palo Alto, California, 94304, United States

  • Stony Brook University Medical Center

    Stony Brook, New York, 11794, United States

  • Strecker Cancer Center-Belpre

    Belpre, Ohio, 45714, United States

  • Summa Health System - Akron Campus

    Akron, Ohio, 44304, United States

  • Swedish American Hospital

    Rockford, Illinois, 61104, United States

  • Swedish Medical Center

    Englewood, Colorado, 80113, United States

  • The Carle Foundation Hospital

    Urbana, Illinois, 61801, United States

  • The Hospital of Central Connecticut

    New Britain, Connecticut, 06050, United States

  • The Mark H Zangmeister Center

    Columbus, Ohio, 43219, United States

  • The Medical Center of Aurora

    Aurora, Colorado, 80012, United States

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • TidalHealth Nanticoke / Allen Cancer Center

    Seaford, Delaware, 19973, United States

  • Toledo Clinic Cancer Centers-Bowling Green

    Bowling Green, Ohio, 43402, United States

  • Toledo Clinic Cancer Centers-Maumee

    Maumee, Ohio, 43537, United States

  • Toledo Clinic Cancer Centers-Monroe

    Monroe, Michigan, 48162, United States

  • Toledo Clinic Cancer Centers-Oregon

    Oregon, Ohio, 43616, United States

  • Toledo Clinic Cancer Centers-Toledo

    Toledo, Ohio, 43623, United States

  • Toledo Community Hospital Oncology Program CCOP

    Toledo, Ohio, 43617, United States

  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor

    Ann Arbor, Michigan, 48106, United States

  • Trinity Health Saint Joseph Mercy Oakland Hospital

    Pontiac, Michigan, 48341, United States

  • Trinity Health Saint Mary Mercy Livonia Hospital

    Livonia, Michigan, 48154, United States

  • Trinity Medical Center

    Moline, Illinois, 61265, United States

  • UI Health Care Mission Cancer and Blood - Des Moines Clinic

    Des Moines, Iowa, 50309, United States

  • UI Health Care Mission Cancer and Blood - Laurel Clinic

    Des Moines, Iowa, 50314, United States

  • UI Health Care Mission Cancer and Blood - West Des Moines Clinic

    Clive, Iowa, 50325, United States

  • UPMC Hillman Cancer Center Erie

    Erie, Pennsylvania, 16505, United States

  • UW Health Carbone Cancer Center Rockford

    Rockford, Illinois, 61114, United States

  • United Hospital

    Saint Paul, Minnesota, 55102, United States

  • Unity Hospital

    Fridley, Minnesota, 55432, United States

  • University Medical Center of Southern Nevada

    Las Vegas, Nevada, 89102, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida, 33136, United States

  • University of Michigan Health - Sparrow Lansing

    Lansing, Michigan, 48912, United States

  • University of New Mexico Cancer Center

    Albuquerque, New Mexico, 87106, United States

  • University of Texas Health Science Center at San Antonio

    San Antonio, Texas, 78229, United States

  • University of Texas Health Science Center at Tyler

    Tyler, Texas, 75708, United States

  • University of Toledo

    Toledo, Ohio, 43614, United States

  • University of Wisconsin Carbone Cancer Center - Johnson Creek

    Johnson Creek, Wisconsin, 53038, United States

  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin, 53792, United States

  • VA Palo Alto Health Care System

    Palo Alto, California, 94304, United States

  • Veterans Adminstration New Jersey Health Care System

    East Orange, New Jersey, 07018-1095, United States

  • Virtua Memorial

    Mount Holly, New Jersey, 08060, United States

  • WellSpan Health-York Hospital

    York, Pennsylvania, 17403, United States

  • West Michigan Cancer Center

    Kalamazoo, Michigan, 49007, United States

  • West Virginia University Charleston Division

    Charleston, West Virginia, 25304, United States

  • West Virginia University Healthcare

    Morgantown, West Virginia, 26506, United States

  • Western States Cancer Research NCORP

    Denver, Colorado, 80222, United States

  • Wheeling Hospital/Schiffler Cancer Center

    Wheeling, West Virginia, 26003, United States

  • Wichita NCI Community Oncology Research Program

    Wichita, Kansas, 67214, United States

  • Woodland Cancer Care Center

    Michigan City, Indiana, 46360, United States

  • York Hospital

    York Village, Maine, 03909, United States

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