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New brain scan technique may predict memory loss after epilepsy surgery

NCT ID NCT03094312

Knowledge-focused Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a special brain imaging method called dynamic spectral imaging (ISD) can predict if someone will have memory or thinking problems after epilepsy surgery. Researchers will map brain activity during cognitive tasks in 50 adults with epilepsy who are already scheduled for brain surgery. The goal is to see if certain brain signals can help surgeons avoid removing areas important for thinking.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dynamic Spectral Imaging (ISD) - a brain mapping procedure
What this could lead to
If successful, this could help doctors better predict and avoid cognitive problems after epilepsy surgery, making surgery safer for patients.
What could go wrong
This is a small, early-stage study (50 participants) that is only looking for patterns, not testing a treatment. The results may not apply to all epilepsy patients or lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2017

Expected to finish

Jan 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patient adult (18-65 y/o) without legal protection measures * Patient with a drug-resistant focal epilepsy * Patient with a SEEG exploration as part of pre-surgical assessment of epilepsy * patient with a consent form signed * Intellectual capacities compatible with cognitive tasks and the signing of informed consent * Affiliation to the social security Exclusion Criteria: * Pregnant women: this is already a contraindication to the realization of a SEEG study * Subjects under 18 years of age or over 65 years of age * Patient not suffering from EFPR, or not scheduled for SEEG * Intellectual capacities incompatible with the cognitive tasks and / or the signature of a consent

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction epilepsy focal epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Epilepsy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospices Civils de Lyon

    RECRUITING

    Bron, 69500, France

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