New study tracks EoE in kids to uncover disease patterns
NCT ID NCT03980886
First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This study observes children with eosinophilic esophagitis (EoE) to understand how their symptoms, endoscopy findings, and inflammatory markers change over time during standard care. Researchers will collect data from up to 1,500 participants during routine clinic and endoscopy visits. The goal is to learn more about the natural history of EoE, not to test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2019
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The majority of patients who are diagnosed with EoE or suspected EoE at RCHSD/UCSD
- Ages
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1 year to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have a known EoE diagnosis * Complain of dysphagia, vomiting, or abdominal pain, especially if recalcitrant to acid blocking therapy (but does not have to be recalcitrant to acid blocking medications) * Present with food impaction * Present with esophageal stricture * Have characteristic endoscopic findings of EoE of pallor, linear furrows, lichenification, white plaques, or concentric rings Exclusion Criteria: * None
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Rady Children's Hospital San Diego
RECRUITINGSan Diego, California, 92123, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A Super-Microscope could spot acid reflux in Kids—Without guesswork?
- Swallowable sponge could replace endoscopy for esophagitis monitoring
- Blood tests may replace scopes for EoE diagnosis
- Massive new registry aims to crack the code on mysterious gut disorders
- 300 kids with EoE enrolled in landmark database study
- Could ditching milk soothe a painful esophagus? new trial tests Diet-Only approach