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New drug combo targets Hard-to-Treat prostate cancer

NCT ID NCT02522715

First seen Mar 02, 2026 · Last updated Jun 11, 2026 · Updated 11 times

Summary

This study tests a combination of two drugs—cabazitaxel (a chemotherapy) and enzalutamide (a hormone blocker)—in people with prostate cancer that has spread and stopped responding to standard hormone therapy. The goal is to find the safest dose and see if the combination can lower PSA levels, a marker of cancer activity. About 37 participants are enrolled in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97239, United States

  • Portland VA Medical Center

    Portland, Oregon, 97239, United States

  • Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.