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Kidney stone breakthrough? study tests gentler start to shock wave therapy

NCT ID NCT07334236

Disease control Sponsor: mohammed Abdelhafez Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two methods of using shock waves to break up kidney stones. One method uses the same energy level throughout, while the other starts with low energy and gradually increases it. The goal is to see which approach clears stones more completely and requires fewer repeat treatments. The trial will involve 100 adults with kidney stones up to 2 cm in size.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Extracorporeal shock wave lithotripsy (ESWL) procedure
What this could lead to
If successful, this could show that starting with low energy and gradually increasing it (energy ramping) clears kidney stones better than using the same energy level throughout, potentially reducing the number of treatments needed.
What could go wrong
This is a small, early-stage trial with only 100 participants, so results may not apply to everyone. The study hasn't started yet, and there is no guarantee that energy ramping will be more effective or safer than the standard approach.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults ≥18 years. * Radiopaque renal or proximal/mid ureteral stone ≤20 mm. * eGFR ≥60 mL/min/1.73 m². * Fit for ESWL. * Able to give informed consent and complete follow up. Exclusion Criteria: * • Pregnancy. * Active, untreated UTI. * Uncorrected bleeding disorder or anticoagulation that cannot be stopped. * Prior ipsilateral renal surgery. * Non radio-opaque stone without reliable imaging. * Inability to tolerate ESWL or required anesthesia.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Renal calculi

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag university Hospital

    Sohag, 82511, Egypt

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