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Flavored vapes tested as smoking cessation aid – but study ends early

NCT ID NCT07172438

First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 34 times

Summary

This study aimed to see if giving smokers access to different e-cigarette flavors (menthol, non-tobacco, or tobacco) helps them stop smoking regular cigarettes. Over 600 adult smokers were assigned to different flavor groups and tracked for 13 weeks. However, the trial was terminated early, so the full results are not available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • C&C-Arlington

    Arlington, Texas, 76015, United States

  • C&C-Fort Smith

    Fort Smith, Arkansas, 72908, United States

  • C&C-Humble

    Humble, Texas, 77338, United States

  • C&C-Lombard

    Lombard, Illinois, 60148, United States

  • C&C-Mesquite

    Mesquite, Texas, 75150, United States

  • C&C-Philadelphia

    Philadelphia, Pennsylvania, 19154, United States

  • C&C-Plantation

    Plantation, Florida, 33388, United States

  • C&C-Richmond Heights

    St Louis, Missouri, 63117, United States

  • C&C-San Antonio

    San Antonio, Texas, 78216, United States

  • C&C-San Antonio

    San Antonio, Texas, 78224, United States

  • C&C-Sebring

    Sebring, Florida, 33870, United States

  • C&C-Tallahassee

    Tallahassee, Florida, 32301, United States

  • C&C-Tampa

    Clearwater, Florida, 33761, United States

  • C&C-Troy

    Troy, Michigan, 48083, United States

  • CRG Test America-Grapevine

    Grapevine, Texas, 76051, United States

  • CRG Test America-Ormond Beach

    Ormond Beach, Florida, 32174, United States

  • CRG Test America-Pembroke Pines

    Miami, Florida, 33026, United States

  • CRG Test America-Phoenix

    Chandler, Arizona, 85226, United States

  • CRG Test America-St. Peters

    City of Saint Peters, Missouri, 63376, United States

  • CRG Test America-Tampa

    Tampa, Florida, 33609, United States

  • Research America Orlando

    Altamonte Springs, Florida, 32701, United States

  • Sago Dallas

    Dallas, Texas, 75254, United States

  • Sago Houston

    Houston, Texas, 77027, United States

  • Sago Orlando

    Maitland, Florida, 32751, United States

  • Sago Philadelphia

    Philadelphia, Pennsylvania, 19103, United States

  • Sago St. Louis

    St Louis, Missouri, 63131, United States

  • Southern Solutions Knoxville

    Knoxville, Tennessee, 37922, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

electronic nicotine delivery system (ENDS) with various e-liquid flavors

What this could lead to

If successful, this could show that offering a choice of flavors in e-cigarettes helps more smokers switch away from combustible cigarettes.

What could go wrong

The study was terminated early, so we may not get clear answers. Also, e-cigarettes carry their own health risks and may not help everyone quit.

Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Tobacco Smoking Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.