Period blood may hold key to endometriosis diagnosis
NCT ID NCT06245512
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to find markers in menstrual blood that can diagnose endometriosis, a painful condition affecting many women. Researchers will compare menstrual blood from 250 women with and without endometriosis, and also look at changes after surgery. If successful, this could lead to a simple, non-invasive test using a menstrual cup.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple, non-invasive test for endometriosis using menstrual blood, making diagnosis easier and faster.
- What could go wrong
- This is an early observational study, not a treatment trial. The markers found may not be reliable enough for widespread use, and results may not apply to all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 250 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2024
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women 18-45 of age with periods
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: For all participants: Women 18-45 of age who * Have their period * Have given their written consent * Have already used a menstrual cup as a method of hygienic protection * Residing or working in Ile de France (Paris Metropolitan area, France) For participants with endometriosis: * diagnosis of endometriosis established by surgery or imaging (ultrasound and/or MRI) * presence of one or more painful symptoms \> 3 on a visual scale (dysmenorrhea and/or dyspareunia and/or chronic pelvic pain) and/or infertility * for the surgery subgroup: planned surgery in the next 3 months For participants without endometriosis: * painful symptoms \< or equal to 3 on a visual scale (for dysmenorrhea and dyspareunia and chronic pelvic pain), * absence of intense period pain in adolescence (leading to taking pills to control this pain and/or peri-menstrual school absenteeism) Exclusion Criteria: For all participants: * Autoimmune diseases * Chronic diseases other than endometriosis (diabetes, hypertension) * A person who is the subject of a judicial safeguard measure (by declaration) * Infectious diseases (HIV, HBV, if known) * History of menstrual toxic shock syndrome For patients with endometriosis: * endometriosis surgery within the last 3 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hopital Cochin
RECRUITINGParis, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Pre-Surgery pelvic floor therapy stop endometriosis pain after the operation?
- Appendix: the hidden driver of endometriosis pain?
- Allergy pill put to the test against endometriosis pain
- Can ultrasound and tissue clues reveal which endometriosis lesions carry cancer risk?
- Can AI personalize exercise to ease pelvic pain?
- Can AI learn to spot endometriosis and fibroids on ultrasound?