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Study questions best surgery for High-Risk endometrial cancer

NCT ID NCT06790004

Knowledge-focused Sponsor: Azienda USL Reggio Emilia - IRCCS Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks back at 700 patients with endometrial cancer to compare two surgical approaches: minimally invasive surgery (laparoscopy) and open surgery (laparotomy). The goal is to see which method is safer and leads to better long-term outcomes, especially for patients at higher risk of recurrence. Researchers will examine complications, survival, and cancer return rates.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors choose the best surgical approach for different stages of endometrial cancer, potentially improving recovery and survival.
What could go wrong
This is an observational study looking back at past cases, not a controlled experiment. Results may be influenced by factors other than the surgery type, and cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 700 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who underwent laparoscopic or laparotomic surgery for Type I or Type II endometrial cancer in the Emilia-Romagna region between 2000 and 2020

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with a diagnosis of endometrial cancer who underwent surgical treatment between 2000 and 2020 Exclusion Criteria: * Patients with other types of tumors (e.g., cervical or ovarian cancer). * Patients for whom surgical and/or post-operative data are unavailable. * Patients with a follow-up period of less than 6 months. * Patients who refuse to provide informed consent.

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Conditions

The condition(s) this trial relates to.

endometrial carcinoma endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometrial carcinoma

Contacts and locations

Locations

  • AOU Parma

    Parma, Italy

  • Azienda Ospedaliera- Universitaria Arcispedale Sant'Anna Ferrara

    Ferrara, Italy

  • Azienda USL IRCCS di Reggio Emilia

    Reggio Emilia, RE, 42123, Italy

  • IRCCS - AOU Bologna

    Bologna, Italy

  • Ospedale Morgagni - Pierantoni

    Forlì, Italy

  • Ospedale di Rimini, AUSL Romagna

    Rimini, Italy

  • Policlinico Sant'Orsola - Malpighi

    Bologna, Italy

  • Policlinico di Modena

    Modena, 41125, Italy

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