Azienda Usl Reggio Emilia - Irccs

This study compares two ways to remove large, flat colon growths (LST-G type) that can turn into cancer. About 282 adults will be randomly assigned to get either standard snare removal (EMR) or a more precise dissection (ESD). The goal is to see which method better prevents the g…

This study is for people with advanced colorectal cancer that has a certain genetic makeup (RAS/BRAF wild type) in the tumor but shows a different genetic change (RAS mutation) in a blood test. The goal is to see if a combination of chemotherapy (FOLFIRI) plus a drug called bevac…

This study tests whether a simple card game, called the Go Wish Game, can help people with advanced blood cancers or solid tumors talk about their end-of-life priorities with their doctors. About 75 adults will play the game and then fill out advance care planning documents. The …

This study follows 150 people with early-stage Parkinson's disease to see how symptoms like walking problems and thinking changes differ between two types: one that starts in the brain and one that starts in the body. Participants will have yearly check-ups, brain scans, and test…

This study follows 50 cancer survivors who visit the MO.RE clinic to see how their physical activity levels change over time. The clinic offers personalized advice and support to help patients overcome barriers like fatigue or lack of motivation. The goal is to learn what works b…

This study looks back at medical records of 4,500 adults who had a mild head injury and a brain scan in the emergency room. The goal is to see how often serious problems like bleeding in the brain happen, and to compare two checklists doctors use to decide who needs a scan. The r…

This study aims to create and test a new questionnaire for caregivers to identify hip pain in children with quadriplegia who cannot speak. Researchers will work with experts and parents to develop the tool, then test it with 100 caregivers. The goal is to improve pain detection a…

This study looks at 60 people with early blood conditions (MGUS or SMM) that can sometimes turn into multiple myeloma, a type of blood cancer. Researchers will use advanced genetic and immune testing to find clues that predict progression. The goal is to better identify high-risk…

This study reviews past medical records of 2,000 adults who had an endoscopic procedure to remove cancerous or precancerous growths in the esophagus, stomach, duodenum, colon, or rectum. The goal is to compare different removal techniques and see how well they work and how safe t…

This study is looking for genetic targets in ovarian cancer, especially a common and aggressive type called high-grade serous ovarian carcinoma. Researchers will use computer models, lab tests on tissue samples, and experiments on cancer cells to understand how certain genes and …

This study looks at the immune system inside malignant pleural mesothelioma tumors. Researchers want to understand why immunotherapy doesn't work for many patients. They will analyze tumor samples from 300 adults to find patterns that could help doctors choose better treatments i…

This study looks at a rare event where an aggressive lymphoma (DLBCL) comes back as a slower-growing type. Researchers will review medical records of 50 adults to understand how often this happens, what treatments work best, and how long people live. The goal is to gather informa…

This study involves 1,500 patients getting PET/CT scans or nuclear medicine therapy. Researchers will use AI and new measurement tools to detect when radioactive drugs leak out of the vein during injection. The goal is to improve safety and make sure the images are accurate, even…

This study looks at a very rare type of ovarian cancer called primary ovarian leiomyosarcoma. Researchers will collect information from past and new cases to understand how it is treated and what happens to patients. The goal is to create better guidelines for doctors. No new tre…