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Can a better crown design save Root-Treated teeth?

NCT ID NCT04604314

Disease control Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial studies how the shape of a tooth preparation affects the fit and long-term success of ceramic endocrowns—a type of crown that replaces the top of a tooth after root canal treatment. Researchers will compare different preparation designs using a high-strength ceramic material (CEREC Tessera) bonded with a special adhesive. The goal is to see which design leads to fewer failures, less staining, and better retention over five years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
CEREC Tessera ceramic endocrown
What this could lead to
If successful, this could help dentists choose the best preparation design for durable, long-lasting ceramic crowns on root-treated molars.
What could go wrong
This is a small, early-stage trial with only 69 participants, and results may not apply to all patients or teeth. Crowns could still fail or require replacement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

69 people

The number who actually took part.

Started

Dec 2020

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 110 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Subject in need of final restoration following molar endodontic therapy 2. Subject age 18 or above - Exclusion Criteria: 1. Teeth with remaining symptoms following endodontic therapy 2. Teeth which have experienced endodontic complications to include treated perforations, internal or external resorption, or separated endodontic files. 3. Teeth with exposure of the root canal filling material to the oral environment for greater than two weeks 4. Teeth diagnosed with symptoms of incomplete tooth fracture 5. Teeth with no adjacent or opposing tooth 6. Teeth serving as an abutment for fixed or removable dental prostheses 7. Subjects with uncontrolled bruxism or parafunctional habits 8. Subject has known allergies to any product used in this study 9. Subject will not be available for the study duration of 5 years 10. Subjects with significant untreated dental disease to include periodontitis and rampant caries 11. Women who self-report that they are pregnant or lactating \-

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Conditions

The condition(s) this trial relates to.

Tooth, Nonvital

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endodontically treated teeth

Contacts and locations

Locations

  • School os Dentistry

    Ann Arbor, Michigan, 48109, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.