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3D-Printed crowns take on milled crowns in dental showdown

NCT ID NCT07633574

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two ways of making dental crowns for back teeth that have had root canals: 3D-printing from a ceramic-filled resin versus milling from a ceramic block. Sixty adults will receive one of these crowns and be checked for fractures, fit, and color over two years. The goal is to see which method produces more durable and reliable restorations.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dental crown (3D-printed ceramic-filled photopolymer resin or CAD/CAM milled hybrid nano-ceramic)
What this could lead to
If successful, this could show that 3D-printed crowns are as good as or better than milled ones, offering a faster, cheaper option for restoring damaged back teeth.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Crowns could chip, break, or discolor over the 24-month study period.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 25-45 years, male or female * Endodontically treated molar tooth with radiographically confirmed treatment success and no clinical signs of failure * Sufficient remaining coronal structure for endocrown preparation: minimum three walls, wall thickness 1.5 mm or greater, pulp chamber depth 3 mm or greater, supragingival preparation margins * Completely erupted tooth with intact periodontal support * Minimum of 20 occluding teeth * Satisfactory oral hygiene status * Capable of providing written informed consent and committed to scheduled follow-up visits Exclusion Criteria: * Diagnosed parafunctional habit or nocturnal bruxism * Uncontrolled systemic illness or physical disability precluding safe participation * Heavy tobacco use * Current or suspected pregnancy * Periapical disease or radiographic signs of endodontic failure * Evidence of pathological tooth wear or occlusal erosion * Moderate-to-severe periodontitis or tooth with hopeless prognosis * Radiographic or clinical evidence of vertical root fracture * Impaired decision-making capacity or anticipated non-compliance

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis Tooth, Nonvital

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental restoration Endodontically treated teeth Tooth, nonvital

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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