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Root canal Patients' bite strength tracked for 4 years

NCT ID NCT07626372

Knowledge-focused Sponsor: Chulalongkorn University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 70 adults aged 20-60 who need root canal treatment on a premolar or molar. Researchers measure how hard they can bite and how force spreads across teeth before treatment, after root canal, after a crown, and up to 4 years later. They also ask about chewing comfort. The goal is to understand how treated teeth recover and compare them to healthy teeth on the other side.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help dentists better plan restorations and improve long-term outcomes for root-canal-treated teeth.
What could go wrong
This is an observational study, not testing a treatment. It only measures changes, so it won't directly improve care. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Oct 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who underwent non-surgical root canal treatment at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Premolars or molars diagnosed with pulp necrosis or previously initiate therapy with normal apical tissues, asymptomatic apical periodontitis, or chronic apical abscess without full coverage restoration. * Adequate remaining tooth structure for cuspal coverage restoration. * Presence of adjacent teeth and functional opposing natural teeth. * No analgesics drug effect at the time of investigation or not have taken analgesics 6 hours ago. Exclusion Criteria: * Patients undergoing other dental treatments during the study period that may interfere with occlusion or bite force distribution, such as orthodontic treatment, jaw surgery, or full mouth restoration. * Received treatments that cause weakness of the jaw and facial muscles, such as botox injections. * History or symptoms of temporomandibular disorders (TMD) * Periodontal disease with second- or third-degree mobility * Teeth presenting crack lines extending into the pulp chamber floor or root canal orifices.

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis suppurative periapical periodontitis Tooth, Nonvital

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endodontically treated teeth

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn university

    Bangkok, 10330, Thailand

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