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New drug combo for rare inflammatory disease falls short

NCT ID NCT04918147

First seen Feb 05, 2026 · Last updated May 20, 2026 · Updated 14 times

Summary

This study tested a drug called elotuzumab combined with prednisone for people with active IgG4-related disease, a rare condition causing swelling and organ damage. The trial was stopped early after enrolling only 8 of the planned 75 participants. The main goal was to check safety, but the early termination means we have limited information on how well the treatment works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Emory Healthcare

    Atlanta, Georgia, 30322, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic: Pulmonary and Critical Care Medicine

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.