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Could eggshells save your teeth? new trial tests natural pulp capping agent

NCT ID NCT07183514

Disease control Sponsor: University of Health Sciences Lahore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares a new material made from eggshells (calcium hydroxyapatite) to a standard one (calcium hydroxide) for protecting the nerve in deep cavities. Fifty-four adults with reversible pulpitis will receive one of the two materials after cavity cleaning. Researchers will check for pain, tooth mobility, and nerve health at 1 and 3 months to see which works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
eggshell-derived calcium hydroxyapatite
What this could lead to
If it works, this could offer a natural, low-cost alternative to standard materials for protecting tooth nerves after cavity treatment.
What could go wrong
This is a small, early-stage trial with only 54 participants and short follow-up (3 months). The eggshell material may not perform as well as the standard treatment, and long-term results are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 54 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2025

An estimate. Start dates often move.

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Teeth with symptoms of reversible pulpitis. 2. Teeth that show positive response on electric pulp testing (EPT). 3. Teeth with caries penetrating up to three-quarters (¾) of dentine without pulp involvement. 4. Healthy cooperative patients of both sexes between 18 to 40 years of age. \- Exclusion Criteria: 1. Necrosed Teeth with radiolucency in the periapical and furcation regions. 2. Tooth with internal and external root resorption. 3. Periodontally compromised tooth. (BPE score 3 and above) 4. Physically and mentally handicapped patients. (ASA score 3 and above)

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Conditions

The condition(s) this trial relates to.

dental caries pulpitis secondary dentine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Indirect pulp cap

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • de'Montmorency college of dentistry Lahore

    Lahore, Punjab Province, 54000, Pakistan

More trials for these conditions

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