Walnuts vs. white chocolate: which snack sharpens your mind?
NCT ID NCT06223672
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether eating walnuts daily for a week can improve thinking and memory in adults who feel their memory is slipping. Participants will eat either walnuts or a white chocolate bar each day, then switch after a break. Researchers will measure brain function and gut health to see if the type of fat matters.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- walnuts
- What this could lead to
- If it works, this could point toward a simple dietary change to help maintain thinking skills in people with early memory concerns.
- What could go wrong
- This is a very small, short-term study (88 people, 1 week per snack). It only looks at immediate effects, not long-term benefits or prevention of dementia.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 88 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subjective cognitive impairment * BMI ≥30 kg/m2 * HbA1C \<6.5% Exclusion Criteria: * Diagnosis og cognitive impairment or dementia * Montreal Cognitive Assessment (MoCA) score of \<26 * Current or previous diagnosis of Diabetes or use of diabetes medications * Current diagnosis of or current treatment of cancer other than non-melanoma skin cancer * Gastrointestinal diseases or disorders (including pancreatic and gastric bypass surgery) where consumption of the study foods would be contraindication or where the disease or disorder could negatively affect nutrient absorption and/or would prevent participants from tolerating the study foods * Hyperthyroidism diagnosis * Food Allergy or intolerances * Any dietary restriction where consumption of the study foods, study meals/snack or meal challenge or any ingredient would be contraindicated * Use of some oil supplements in the past 4 weeks prior to enrolling * Pregnancy and lactation * Inability to access veins for venipuncture * Antibiotic use in the past month * Psychostimulant or nootropic medication use * Current use of supplements or medications for weight loss or following a weight loss program * Severe or uncontrolled autoimmune diseases * Current or previous diagnosis of severe kidney failure, liver cirrhosis and some pulmonary diseases * Heart disease events (including stroke or heart attack) within last 3 months prior to enrollment * Alcohol or drug abuse
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
Locations
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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