Tiny viruses, big impact? study links early gut & lung viruses to preterm lung disease
NCT ID NCT07487259
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 40 premature babies (born before 30 weeks) to see if viruses in their lungs and gut during the first three weeks of life are linked to a serious lung condition called bronchopulmonary dysplasia (BPD). Researchers will collect throat and stool samples to track viral changes and compare babies who develop BPD with those who don't. The goal is to better understand how early viral exposure might influence lung health, which could lead to new ways to predict or prevent BPD.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Neonates hospitalised in the neonatal intensive care unit (NICU) of Lyon University Hospital, France.
- Ages
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Up to 30 weeks
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Birth \< 30 SA * Respiratory support at birth (invasive or non-invasive ventilation, or oxygen supplementation). Exclusion Criteria: * \- Major congenital anomalies of the lung or airways. * Death, transfer or discharge before 36 weeks' postmenstrual age (PMA) (not allowing progression to BPD to be known). * Number of respiratory samples collected \< 3
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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- Could a simple steroid help tiny preemies escape breathing machines?