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Can a simple CT scan catch lung cancer early in HIV smokers?

NCT ID NCT01207986

Diagnosis Sponsor: ANRS, Emerging Infectious Diseases Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether low-dose CT scans can help find lung cancer early in HIV-positive people who are heavy smokers. Researchers scanned 450 participants to see how many had lung cancer and what types were found. The goal was to learn if this screening method is useful for this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low-dose computed tomography (CT) scan
What this could lead to
If successful, this could show that low-dose CT scans are a useful tool for catching lung cancer early in HIV-positive people with a history of heavy smoking.
What could go wrong
This is a small, early pilot study, not a large trial. It only looks at detection rates, not whether earlier diagnosis actually improves survival or reduces harm.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

450 people

The number who actually took part.

Start date

Feb 2011

Finished

Aug 2014

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 40 years * able to give written consent * HIV positive serology * Covered by French Social Security * Nadir L TCD4 \< 350/µl * Rate of LTCD4 \> 100/µl at inclusion * Addiction to smoking \> 20 packages years, active person or deprived since \< 3 years Exclusion Criteria: * patients who suffered from comorbidity * unaffiliated to the social healthy security french system * Presence of an evolutionary cancer * any evolutionary pathology classifying AIDS * Pregnancy * Recent lung infection (\< 2 months) * Be under protection (saving) of justice

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Conditions

The condition(s) this trial relates to.

HIV infectious disease lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV infection Lung cancer

Contacts and locations

Locations

  • Makinson

    Montpellier, 34, France

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Other studies related to the condition(s) this trial covers.