Blood markers could spot sepsis risk early
NCT ID NCT02545478
First seen Apr 16, 2026 · Last updated Jun 23, 2026 · Updated 11 times
Summary
This study is looking at whether early signs of inflammation in the blood can help identify which patients with infections are at risk for serious complications like sepsis. Researchers will follow 4,200 adults with confirmed or suspected infections, as well as healthy controls, to see how well these biomarkers predict death or organ failure within 28 days. The goal is to improve early detection and treatment of severe infections.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
ACTIVE_NOT_RECRUITINGBoston, Massachusetts, 02114, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to better tools for early detection of severe infections, helping doctors intervene sooner and potentially reduce deaths from sepsis.
What could go wrong
This is an observational study, not a treatment trial. It may not directly improve patient outcomes, and the biomarkers might not be accurate enough for widespread use.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.