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New hope for MSA patients: drug may reduce dizzy spells and falls

NCT ID NCT02071459

First seen Apr 11, 2026 · Last updated Jun 18, 2026 · Updated 8 times

Summary

This study tested a drug called droxidopa (L-threo DOPS) in 107 adults with multiple system atrophy (MSA) who experience dizziness or fainting when standing up due to low blood pressure. Participants received either the drug or a placebo for 12 weeks. The goal was to see if the drug could reduce these symptoms and improve daily life. The trial is complete, and results help doctors understand if this treatment is helpful for managing this challenging symptom.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHRU de lille

    Lille, 59037, France

  • CHU Pontchaillou

    Rennes, 35033, France

  • CHU bordeaux

    Bordeaux, France

  • CHU de Clermont-Ferrand

    Clermont-Ferrand, 63000, France

  • CHU de Dijon

    Dijon, 21000, France

  • CHU de Poitiers

    Poitiers, 86021, France

  • CHU de Rouen

    Rouen, 76031, France

  • CHU de limoges

    Limoges, 87042, France

  • Centre hospitalier d'Angers

    Angers, 49933, France

  • Hôpital G. & R. Laennec

    Nantes, 44093, France

  • Hôpital La Timone

    Marseille, 13000, France

  • Hôpital Pitié-Salpétrière

    Paris, 75013, France

  • chu de Strasbourg

    Strasbourg, 67091, France

Conditions

The condition(s) this trial relates to.

Hypotension, Orthostatic multiple system atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.