Can a smartphone program help heavy smokers quit and get lifesaving scans?

NCT ID NCT04691297

Disease control Sponsor: Dana-Farber Cancer Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called ESCAPE that combines counseling, nicotine replacement, digital videos, and lung screening education to help high-risk smokers quit. It involves 153 smokers aged 55-77 with a heavy smoking history. The program is compared to standard care (brief advice and a quitline referral). The goal is to see if the digital approach leads to more people quitting and getting screened for lung cancer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: behavioral counseling, nicotine replacement therapy, digital storytelling videos, and lung screening education
What this could lead to: If successful, this program could help high-risk smokers quit more effectively and increase lung cancer screening rates, potentially reducing lung cancer deaths.
What could go wrong: This is a small Phase II trial with only 153 participants, so results may not apply to everyone. The program's success depends on participants engaging with digital tools, which may not work for all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

153 people

The number who actually took part.

Started

Feb 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 77 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 55 to 77 years of age * No previous history of lung cancer * ECOG performance status \< 2 * ≥ 30 pack year smoking history * Smoke ≥ 5 cigarettes/day * Own a mobile phone with access to a video call application * Has a primary care provider (PCP) * Provide contact information for the PCP * Active health insurance * Has not had LDCT screening * English speaking * Can complete an interview Exclusion Criteria: * Hospitalization for severe mental illness within the last year. * The following special populations will not be included * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Pregnant women * Prisoners

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Conditions

The condition(s) this trial relates to.

Smoking Smoking Cessation Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer screening Smoking Smoking behaviors Smoking cessation Smoking, tobacco

Can a smartphone program help heavy smokers quit and get lifesaving scans?

What the study statuses mean