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Phone app could stop PTSD and pot addiction after assault

NCT ID NCT05989841

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a smartphone-based program called RISE Guide for women who have just been sexually assaulted. The goal is to see if it can reduce anxiety sensitivity and prevent posttraumatic stress disorder (PTSD) and cannabis use disorder (CUD). 68 women who seek emergency care within 72 hours of an assault and use cannabis at least once a week will use the app for 9 weeks. Researchers will measure changes in anxiety and cannabis-related problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
RISE Guide (a smartphone-based cognitive behavioral therapy program)
What this could lead to
If it works, this could provide a practical, scalable way to prevent PTSD and cannabis use disorder in women after sexual assault.
What could go wrong
This is an early Phase 1/2 trial with only 68 participants, so results may not apply to everyone. The intervention is new and may not be effective for all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

About 68 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2024

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Women sexual assault survivors presenting for emergency care \<72 hours post-assault at 1 of our 4 emergency care sites 2. English speakers 3. 18+ years of age 4. Able to provide informed consent 5. Have a smartphone with continuous service \>1 year 6. Report \>1x/weekly cannabis use on a substance use screener 7. Report elevated AS (\>17 on the Anxiety Sensitivity Index-3) Exclusion Criteria: 1. Inability to provide informed consent (e.g., serious injury preventing the ability to hear, speak, or see to consent and participate, or other causes (e.g., diagnosed cognitive deficits, diagnosed dementia, asleep at time of screening)). 2. Prisoner 3. Currently pregnant 4. Lives with assailant and plans to continue to do so 5. Admitted patient 6. No mailing address 7. Previously enrolled 8. No sexual assault nurse examiner (SANE) examination 9. Reporting current plan and intent for suicide or homicide 10. Does not understand written and spoken English

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Harbor Shelter

    RECRUITING

    Smithfield, North Carolina, 27577, United States

  • Hennepin Assault Response Team

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55415, United States

  • SAFE Austin

    RECRUITING

    Austin, Texas, 74103, United States

  • Tulsa Forensic Nursing

    NOT_YET_RECRUITING

    Tulsa, Oklahoma, 74103, United States

  • UNC Chapel Hill

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University Medical Center

    NOT_YET_RECRUITING

    Las Vegas, Nevada, 89102, United States

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