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Digital reminiscence app aims to lift mood in dementia

NCT ID NCT07237009

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether daily 10-15 minute personalized reminiscence sessions delivered by a digital app can improve symptoms like apathy and depression in older adults with mild neurocognitive disorders. Eighty participants over 60 will use the app for 25 days, with a caregiver helping to personalize memories. The goal is to see if this approach can boost mood, motivation, sleep, and quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be recruited during routine visits at five French university hospital geriatrics/memory clinics. The source population comprises older adults followed in these services who live mainly at home or in hospital-based residential settings. The study focuses exclusively on patients with mild neurocognitive disorder or mild dementia, and includes individuals with mild depression.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men and women over 60 years of age. * DSM-5 diagnosis: Early stage of major neurocognitive disorders or MCI (Mild Cognitive Impairment) including all underlying causes. * Have a Mini-Mental State Exam score of 21 ≤ MMSE ≤ 28. * Presence of mild or moderate depression, or presence of mild or moderate apathy, or presence of both * Displays the necessary physical and cognitive abilities, without major limitations compromising interaction with the digital tool. * Having voluntarily and informedly agreed to participate in the study (signed written consent). * Subject's ability to hear and see the digital tool's stimuli (tests integrated into the tool). * Patients with access to an Apple device (smartphone or tablet), either personal or provided by the sponsor, running iOS version 16 or higher, with internet access. * Patient has at least one close referent who declares their wish to contribute to the collection of biographical information via the digital messaging group. * Subjects covered by a social security scheme. Exclusion Criteria: * Patients with moderate or severe dementia (MMSE score ≤ 20) because implicit memory recall is less effective in moderate or severe stages for people with PWD. * Presence of major psychiatric disorders (e.g., schizophrenia, severe major depressive episode, bipolar disorder). * Major hearing or visual impairments. * History of premorbid intellectual disability. * Patients under guardianship, conservatorship, or legal protection. * Patients who have already used the Lilia app * Participating simultaneously in another study involving human subjects, a clinical investigation, or a therapeutic trial for the entire duration of the study. * Patients who have received a new treatment related to neurocognitive disorders (medication) during the 3 months prior to the inclusion visit.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • APHP Hôpitaux universitaires Paris centre.

    NOT_YET_RECRUITING

    Paris, 75013, France

  • CHU Angers, Service médecine gériatrique.

    RECRUITING

    Angers, 49 933, France

  • CHU DE TOURS, Pôle Vieillissement, Hôpital Bretonneau.

    RECRUITING

    Tours, 37044, France

  • Centre Hospitalier Universitaire de Nice - Institut Claude Pompidou, Centre Mémoire de Ressources et de Recherches (CM2R)

    RECRUITING

    Nice, 06100, France

  • Limoges University Hospital Center - Dupuytren Hospital], Geriatric medicine department

    RECRUITING

    Limoges, 87042, France

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