Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can brain scans unlock the mystery of apathy?

NCT ID NCT04757220

Knowledge-focused Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This study investigates why people with schizophrenia or depression often experience apathy—a loss of motivation and goal-directed behavior. Researchers will use cognitive tasks and EEG brain recordings to examine three distinct forms of apathy: executive, emotional, and initiative. By comparing brain activity and performance across these subtypes, they hope to uncover the underlying cognitive and neural mechanisms, which could eventually lead to better treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cognitive tasks with EEG recording
What this could lead to
If successful, this could lead to better understanding of apathy's subtypes, potentially guiding future targeted treatments.
What could go wrong
This is an observational study, so it won't directly test treatments. The findings may not apply to all patients or lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 144 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2022

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion criteria (all subjects): * age between 18 and 60 years * men or women volunteers, hospitalized or not * subject affiliated to an health insurance * subject having signed an informed consent Inclusion criteria (for schizophrenic patients): \- presence of DSM-V TR criteria for schizophrenia (American Psychiatric Association, 1994) Inclusion criteria (for depressive patients): \- presence of DSM-V TR criteria for depression (American Psychiatric Association, 1994) Exclusion Criteria: * a major or non stabilized somatic disorder * medical history likely to affect cerebral anatomy or linked to an abnormality (neonatal distress, neurochirurgical intervention, neurological disorders, stroke attack) * any disorders involved in the use of a psycho-active substance (as defined by the DSM-IV) * sensory disabling impairments, and specifically visual acuity \< 8 * general anaesthesia during the 3 months before the study * pregnancy (declared by the subject) * persons in an emergency situation * persons deprived in any way of their liberty * persons in period of exclusion in an other protocol Exclusion criteria (for controls): \- use of psychotropic substance during the 3 weeks before the study Exclusion criteria (for patients): \- use of benzodiazepines

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for APATHY are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

depressive disorder Lethargy schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APATHY

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Service de Psychiatrie, Hôpital Civil, Hôpitaux Universitaires de Strasbourg

    RECRUITING

    Strasbourg, 67091, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.