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Fatty foods may fuel inflammation in seniors, study finds

NCT ID NCT05327868

Knowledge-focused Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how eating a high-fat diet for 5 days affects inflammation in older adults (ages 50-79) with normal weight or obesity. Researchers measured blood markers and gut bacteria to see if a high-fat diet causes more inflammation than a low-fat diet. The goal was to understand how body weight and diet together influence inflammation in aging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Mar 2022

Finished

Feb 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 79 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men or Women * Age 50-79 years (only postmenopausal women \> 2 years) * Body mass index (20-25 kg/m2; and 30-40 kg/m2)\* Exclusion Criteria: * Diagnosed with, active, or history of liver cirrhosis, chronic or persisting hepatitis * Diagnosed with, active, or history of cancer * History of gastrointestinal disease or surgical procedure for weight loss. * Diagnosed with immune diseases, type 2 diabetes, pancreatitis, or infectious diseases * Any surgery in the past 6 months * Currently using or have used antibiotics continuously \> 3 days in the past 3 months * Regular use of medications for that affect the gastrointestinal tract, cholecystitis, urinary tract infection, severe organic diseases including coronary heart disease, myocardial infarction, infectious diseases including pulmonary tuberculosis and AIDS * Known allergy or intolerance to any ingredients in the dietary intervention program * Alcohol or illicit drug abuse * Current Smoker or have quit smoking in the past 3 months * Recent colonoscopy (within the previous two months) * Inability to follow any of the experimental diets (including low or high fat diet) or to perform the collections required for this study * Participants will also be excluded if they have extreme dietary habits, extreme levels of physical or athletic activity, or by changes in body weight \>5 lbs. during the last 6 months * Uncontrolled hypertension or uncontrolled hyperlipidemia in abnormal ranges. * Participation in another clinical research trial that may interfere with the results of this study. * As needed, BMI (kg/m2) will be adjusted accordingly for Asian lean and obese definitions

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Conditions

The condition(s) this trial relates to.

Inflammation inflammatory disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dietary fat Inflammation Obesity

Contacts and locations

Locations

  • Rutgers University

    New Brunswick, New Jersey, 08901, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.