Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a steroid or asthma drug ease kidney stone pain?

NCT ID NCT06980727

Symptom relief Sponsor: University of Monastir Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jul 16, 2026 · Updated 3 times

Summary

This study tests whether adding either dexamethasone (a steroid) or terbutaline (an asthma drug) to standard paracetamol provides better pain relief for people with kidney stones in the emergency room. About 300 adults with severe pain will be randomly assigned to one of the two drug combinations or a placebo. The main goal is to see if pain drops by at least half within a few hours.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone and terbutaline
What this could lead to
If it works, this could point toward a better, faster way to manage kidney stone pain in the emergency room.
What could go wrong
This is a single-center trial with 300 participants, so results may not apply to everyone. The drugs also have side effects like heart issues or infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Mar 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Adults aged 18-65 years * Clinical diagnosis of acute renal colic (defined as sudden sharp colicky flank pain with or without radiation to the genitalia or groin, and with or without urinary symptoms) * Pain score of 5 or more measured using the 10-cm NRS scale Exclusion Criteria: * History of cardiovascular, hepatic, renal, or metabolic diseases * Evidence of sepsis or clinical suspicion of urinary tract infection * Hemodynamically unstable (systolic blood pressure \< 90 mmHg) * Uncontrolled diabetes * Pregnancy or breastfeeding * Inability to understand verbal and/or written information * Received any analgesics within 6 hours prior to presentation * Serum potassium \< 3.7 mmol/L * Concomitant use of: Any beta-blockers (including beta-blocker-containing eye drops) Prolonged-release long-acting β-agonists Short-acting β2-agonists within 6 hours prior to presentation * Contraindication to terbutaline use * Known allergy to paracetamol or terbutaline * Abdominal tenderness suggestive of peritoneal inflammation * Clinical suspicion of conditions other than urolithiasis, including: * Abdominal aortic aneurysm * Aortic dissection * History of drug dependence or chronic alcohol consumption

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Acute renal colic due to urolithiasis are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Renal Colic urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Renal colic

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital Fattouma Bourguiba Monastir

    Monastir, Monastir Governorate, 5000, Tunisia

More trials for these conditions

Other studies related to the condition(s) this trial covers.