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Kidney stone pain study reveals how painkillers impact breathing

NCT ID NCT07386288

Symptom relief Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 102 adults with kidney stone pain to see how two common painkillers (dexketoprofen and tramadol) affect breathing and blood flow. Patients received one or both drugs, and their carbon dioxide levels and oxygen were measured for an hour. The goal was to understand if these pain relievers cause any short-term changes in how the body handles pain and breathing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

102 people

The number who actually took part.

Started

Nov 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * A Glasgow Coma Scale score of 15 * Spontaneous respiration * The capacity to provide informed consent Exclusion Criteria: * Pregnancy or breastfeeding * Chronic kidney disease, * Known allergy to study medications, * Chronic respiratory disease, * Hemodynamic instability, * Acute intoxication, * Uncontrolled epilepsy, * Recent monoamine oxidase inhibitor use.

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Conditions

The condition(s) this trial relates to.

Emergencies Renal Colic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Renal colic

Contacts and locations

Locations

  • Ataturk University, Yakutiye Research Hospital

    Yakutiye, Erzurum, 25240, Turkey (Türkiye)

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