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Milder chemo shows promise for HER2+ breast cancer patients

NCT ID NCT07421141

First seen Feb 21, 2026 · Last updated May 01, 2026 · Updated 12 times

Summary

This study tests a less intense chemotherapy combination (paclitaxel, trastuzumab, and pertuzumab) for people with early-stage HER2-positive breast cancer. The goal is to see if this gentler approach works as well as the standard stronger regimen, with fewer side effects. 186 participants are involved, and the main measure is whether the cancer disappears completely by the time of surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • P.A. Hertsen Moscow Oncology Research Institute

    Moscow, 125284, Russia

Conditions

Explore the condition pages connected to this study.