Cold hands, healthy nerves? study tests cryotherapy to block chemo side effect
NCT ID NCT06281925
First seen Mar 13, 2026 · Last updated Jun 22, 2026 · Updated 16 times
Summary
This study tests whether wearing cold gloves during chemotherapy can prevent peripheral neuropathy (nerve damage causing numbness, tingling, or pain) in colon cancer patients. Forty adults with stage III colon cancer who are about to start a common chemo regimen (CAPOX) will be randomly assigned to use cryotherapy gloves or not. The goal is to see if the cold treatment reduces the number of people who develop nerve problems.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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NYU Langone Health
Mineola, New York, 11501, United States
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NYU Langone Health
New York, New York, 10016, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cryotherapy gloves (cold packs in fabric gloves)
What this could lead to
If it works, this could offer a simple, drug-free way to prevent painful nerve damage from chemotherapy, improving quality of life for colon cancer patients.
What could go wrong
This is a small pilot study with only 40 people, and it is currently suspended. The results may not apply to everyone, and the benefit may be small or absent.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.