Freeze and boost: new combo aims to stop breast cancer return

NCT ID NCT03546686

Ongoing Disease control Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Oct 01, 2025 · Last updated May 18, 2026 · Updated 31 times

Summary

This study tests whether freezing the tumor (cryoablation) combined with an immunotherapy drug before surgery can help prevent breast cancer from coming back in women with triple-negative breast cancer. About 51 women who still have cancer after initial chemotherapy will receive this treatment. The main goal is to see if the approach improves how long women live without their cancer returning.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Cedars Sinai Medical Center

Los Angeles, California, 90048, United States
Ohio State University Medical Center

Columbus, Ohio, 43210, United States
Providence Cancer Institute

Portland, Oregon, 97213, United States
UT Southwestern Medical Center

Dallas, Texas, 75390, United States

Conditions

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BREAST CANCER